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WB:itr-1
Contents |
| Species (Taxon ID) | Caenorhabditis elegans (nematode) (taxon:6239) | |
| Gene Name(s) | itr-1 ( synonyms: F33D4.2, dec-4 ) | |
| Protein Name(s) | No Information Provided. | |
| External Links | ||
| WB | WBGene00002173 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000003 |
reproduction |
WB_REF:WBPaper00005654 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00008743 |
P |
From WB |
||
| GO:0000003 |
reproduction |
WB_REF:WBPaper00006395 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00025376 |
P |
From WB |
||
| GO:0000003 |
reproduction |
WB_REF:WBPaper00013501 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00078895 |
P |
From WB |
||
| GO:0000003 |
reproduction |
WB_REF:WBPaper00024681 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00061437 |
P |
From WB |
||
| GO:0000003 |
reproduction |
WB_REF:WBPaper00026608 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00061091 |
P |
From WB |
||
| GO:0000003 |
reproduction |
WB_REF:WBPaper00038381 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00085492 |
P |
From WB |
||
| GO:0001556 |
oocyte maturation |
WB_REF:WBPaper00026932 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00001482 |
P |
From WB |
||
| GO:0005216 |
ion channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
F |
From WB |
|||
| GO:0005220 |
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000493 |
F |
From WB |
|||
| GO:0005220 |
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity |
WB_REF:WBPaper00003693 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From WB |
|||
| GO:0005262 |
calcium channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000699 |
F |
From WB |
|||
| GO:0005515 |
protein binding |
WB_REF:WBPaper00024213 |
IPI: Inferred from Physical Interaction |
WB:WBGene00002148 |
F |
From WB |
||
| GO:0005783 |
endoplasmic reticulum |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000493 |
C |
From WB |
|||
| GO:0005783 |
endoplasmic reticulum |
WB_REF:WBPaper00024544 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
P |
From WB |
|||
| GO:0006816 |
calcium ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000493 |
P |
From WB |
|||
| GO:0006898 |
receptor-mediated endocytosis |
WB_REF:WBPaper00030951 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00071422 |
P |
From WB |
||
| GO:0006936 |
muscle contraction |
WB_REF:WBPaper00003693 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0006936 |
muscle contraction |
WB_REF:WBPaper00024307 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0007204 |
elevation of cytosolic calcium ion concentration |
WB_REF:WBPaper00003693 |
IDA: Inferred from Direct Assay |
P |
From WB |
|||
| GO:0007320 |
insemination |
WB_REF:WBPaper00026608 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00061091 |
P |
From WB |
||
| GO:0007622 |
rhythmic behavior |
WB_REF:WBPaper00003693 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0012501 |
programmed cell death |
WB_REF:WBPaper00004880 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00003168 |
P |
From WB |
||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000493 |
C |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000699 |
C |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003608 |
C |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
C |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR016093 |
C |
From WB |
|||
| GO:0016020 |
membrane |
WB_REF:WBPaper00003819 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
CBS:TMHMM |
C |
From WB |
|||
| GO:0017022 |
myosin binding |
WB_REF:WBPaper00005299 |
IPI: Inferred from Physical Interaction |
WB:WBGene00002348 |
F |
From WB |
||
| GO:0030334 |
regulation of cell migration |
WB_REF:WBPaper00024544 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00088056 |
P |
From WB |
||
| GO:0030421 |
defecation |
WB_REF:WBPaper00003693 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0030421 |
defecation |
WB_REF:WBPaper00004858 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00000802 |
P |
From WB |
||
| GO:0030421 |
defecation |
WB_REF:WBPaper00013501 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00078895 |
P |
From WB |
||
| GO:0030728 |
ovulation |
WB_REF:WBPaper00013501 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00078895 |
P |
From WB |
||
| GO:0030728 |
ovulation |
WB_REF:WBPaper00013501 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00078896 |
P |
From WB |
||
| GO:0034607 |
turning behavior involved in mating |
WB_REF:WBPaper00026608 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00061091 |
P |
From WB |
||
| GO:0042713 |
sperm ejaculation |
WB_REF:WBPaper00026608 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00242483 |
P |
From WB |
||
| GO:0043051 |
regulation of pharyngeal pumping |
WB_REF:WBPaper00006314 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00001196 |
P |
From WB |
||
| GO:0043051 |
regulation of pharyngeal pumping |
WB_REF:WBPaper00006314 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00242483 |
P |
From WB |
||
| GO:0048598 |
embryonic morphogenesis |
WB_REF:WBPaper00005235 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0048609 |
multicellular organismal reproductive process |
WB_REF:WBPaper00004858 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00000802 |
P |
From WB |
||
| GO:0051489 |
regulation of filopodium assembly |
WB_REF:WBPaper00024544 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00088056 |
P |
From WB |
||
| GO:0055085 |
transmembrane transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
P |
From WB |
|||
| GO:0060179 |
male mating behavior |
WB_REF:WBPaper00026608 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0070588 |
calcium ion transmembrane transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000699 |
P |
From WB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
- ↑ Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
- ↑ Xu X et al. (2005) Linking integrin to IP(3) signaling is important for ovulation in Caenorhabditis elegans. FEBS Lett 579: 549-53 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Gower NJ et al. (2005) Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males. Mol Biol Cell 16: 3978-86 PubMed GONUTS page
- ↑ Green RA et al. (2011) A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell 145: 470-82 PubMed GONUTS page
- ↑ Corrigan C et al. (2005) Eph and NMDA receptors control Ca2+/calmodulin-dependent protein kinase II activation during C. elegans oocyte meiotic maturation. Development 132: 5225-37 PubMed GONUTS page
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 Dal Santo P et al. (1999) The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans. Cell 98: 757-67 PubMed GONUTS page
- ↑ Walker DS et al. (2004) IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans. Mol Biol Cell 15: 3073-82 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Thomas-Virnig CL et al. (2004) The inositol 1,4,5-trisphosphate receptor regulates epidermal cell migration in Caenorhabditis elegans. Curr Biol 14: 1882-7 PubMed GONUTS page
- ↑ Balklava Z et al. (2007) Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nat Cell Biol 9: 1066-73 PubMed GONUTS page
- ↑ Yin X et al. (2004) Inositol 1,4,5-trisphosphate signaling regulates rhythmic contractile activity of myoepithelial sheath cells in Caenorhabditis elegans. Mol Biol Cell 15: 3938-49 PubMed GONUTS page
- ↑ Xu K et al. (2001) Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum. Neuron 31: 957-71 PubMed GONUTS page
- ↑ Baylis HA et al. (1999) Inositol 1,4,5-trisphosphate receptors are strongly expressed in the nervous system, pharynx, intestine, gonad and excretory cell of Caenorhabditis elegans and are encoded by a single gene (itr-1). J Mol Biol 294: 467-76 PubMed GONUTS page
- ↑ Walker DS et al. (2002) A direct interaction between IP(3) receptors and myosin II regulates IP(3) signaling in C. elegans. Curr Biol 12: 951-6 PubMed GONUTS page
- ↑ 17.0 17.1 Park BJ et al. (2001) Calreticulin, a calcium-binding molecular chaperone, is required for stress response and fertility in Caenorhabditis elegans. Mol Biol Cell 12: 2835-45 PubMed GONUTS page
- ↑ 18.0 18.1 Bastiani CA et al. (2003) Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle. Genetics 165: 1805-22 PubMed GONUTS page
- ↑ Walker DS et al. (2002) Regulated disruption of inositol 1,4,5-trisphosphate signaling in Caenorhabditis elegans reveals new functions in feeding and embryogenesis. Mol Biol Cell 13: 1329-37 PubMed GONUTS page
