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WB:hsp-60

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) hsp-60 ( synonyms: Y22D7AL.5 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00002025

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00024497
PMID:15489339[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00027606
WB:WBPhenotype:0000689

P

From WB

GO:0000302

response to reactive oxygen species

WB_REF:WBPaper00024269
PMID:15280428[2]

IEP: Inferred from Expression Pattern

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00024269
PMID:15280428[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00024269
PMID:15280428[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084198
WB:WBPhenotype:0000059

P

From WB

GO:0005524

ATP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002423

F

From WB

GO:0005524

ATP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR018370

F

From WB

GO:0005737

cytoplasm

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001844

C

From WB

GO:0005737

cytoplasm

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR018370

C

From WB

GO:0005739

mitochondrion

WB_REF:WBPaper00028954
PMID:17189267[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0006457

protein folding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR018370

P

From WB

GO:0007005

mitochondrion organization

WB_REF:WBPaper00027723
PMID:16816413[6]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0008134

transcription factor binding

WB_REF:WBPaper00031084
PMID:17925224[7]

IPI: Inferred from Physical Interaction

WB:WBGene00022861

F

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00024269
PMID:15280428[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00055670
WB:WBPhenotype:0000050

P

From WB

GO:0030968

endoplasmic reticulum unfolded protein response

WB_REF:WBPaper00035985
PMID:20188671[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084611
WB:WBPhenotype:0001719

P

From WB

GO:0030968

endoplasmic reticulum unfolded protein response

WB_REF:WBPaper00035985
PMID:20188671[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084612
WB:WBPhenotype:0001719

P

From WB

GO:0030968

endoplasmic reticulum unfolded protein response

WB_REF:WBPaper00035985
PMID:20188671[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084615
WB:WBPhenotype:0001719

P

From WB

GO:0030968

endoplasmic reticulum unfolded protein response

WB_REF:WBPaper00035985
PMID:20188671[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084616
WB:WBPhenotype:0001719

P

From WB

GO:0030968

endoplasmic reticulum unfolded protein response

WB_REF:WBPaper00035985
PMID:20188671[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084617
WB:WBPhenotype:0001719

P

From WB

GO:0034514

mitochondrial unfolded protein response

WB_REF:WBPaper00024269
PMID:15280428[2]

IEP: Inferred from Expression Pattern

P

From WB

GO:0040007

growth

WB_REF:WBPaper00024269
PMID:15280428[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084198
WB:WBPhenotype:0000059

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00024269
PMID:15280428[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084198
WB:WBPhenotype:0000031

P

From WB

GO:0042026

protein refolding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001844

P

From WB

GO:0044267

cellular protein metabolic process

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002423

P

From WB

GO:0051082

unfolded protein binding

WB_REF:WBPaper00024269
PMID:15280428[2]

ISS: Inferred from Sequence or Structural Similarity

F

From WB

NOT

GO:0009408

response to heat

WB_REF:WBPaper00024269
PMID:15280428[2]

IEP: Inferred from Expression Pattern

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Rual JF et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Yoneda T et al. (2004) Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones. J Cell Sci 117: 4055-66 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  5. Kimura K et al. (2007) Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans. J Biol Chem 282: 5910-8 PubMed GONUTS page
  6. Benedetti C et al. (2006) Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response. Genetics 174: 229-39 PubMed GONUTS page
  7. Haynes CM et al. (2007) ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans. Dev Cell 13: 467-80 PubMed GONUTS page
  8. Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 9.4 Haynes CM et al. (2010) The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol Cell 37: 529-40 PubMed GONUTS page
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