WB:hlh-1

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Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000003	reproduction	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064772 WB:WBPhenotype:0000688	P	From WB
	GO:0000003	reproduction	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064830 WB:WBPhenotype:0000688	P	From WB
	GO:0002119	nematode larval development	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064717 WB:WBPhenotype:0000054	P	From WB
	GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	WB_REF:WBPaper00001358 PMID:2175254^[2]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P10085	F	From WB
	GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	WB_REF:WBPaper00032967 PMID:19261701^[3]	IDA: Inferred from Direct Assay		F	From WB
	GO:0005634	nucleus	WB_REF:WBPaper00001358 PMID:2175254^[2]	IDA: Inferred from Direct Assay		C	From WB
	GO:0006357	regulation of transcription from RNA polymerase II promoter	WB_REF:WBPaper00001358 PMID:2175254^[2]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P10085	P	From WB
	GO:0006366	transcription from RNA polymerase II promoter	WB_REF:WBPaper00034761 PMID:19632181^[4]	IDA: Inferred from Direct Assay		P	From WB
	GO:0007517	muscle organ development	WB_REF:WBPaper00001358 PMID:2175254^[2]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P10085	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025054 PMID:15791247^[5]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00038910 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069547 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069548 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069549 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069550 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069551 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069552 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069553 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069554 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069555 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069556 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069557 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069558 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069559 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069560 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069561 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00025190 PMID:15892873^[6]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00069562 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064717 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064830 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00028381 PMID:16884526^[7]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00086369 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00028381 PMID:16884526^[7]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00086373 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00028381 PMID:16884526^[7]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00086376 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00028381 PMID:16884526^[7]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00086379 WB:WBPhenotype:0000050	P	From WB
	GO:0010171	body morphogenesis	WB_REF:WBPaper00004597 PMID:11223248^[8]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00076022 WB:WBPhenotype:0000583	P	From WB
	GO:0010171	body morphogenesis	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064717 WB:WBPhenotype:0000535	P	From WB
	GO:0040010	positive regulation of growth rate	WB_REF:WBPaper00027756 PMID:16845399^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064717 WB:WBPhenotype:0000031	P	From WB
	GO:0040011	locomotion	WB_REF:WBPaper00006395 PMID:14551910^[9]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00024379 WB:WBPhenotype:0000643	P	From WB
	GO:0040011	locomotion	WB_REF:WBPaper00006395 PMID:14551910^[9]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00027142 WB:WBPhenotype:0000643	P	From WB
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	WB_REF:WBPaper00032967 PMID:19261701^[3]	IDA: Inferred from Direct Assay		P	From WB
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	WB_REF:WBPaper00032967 PMID:19261701^[3]	IMP: Inferred from Mutant Phenotype	WB:WBVar00051372	P	From WB
	GO:0051146	striated muscle cell differentiation	WB_REF:WBPaper00001975 PMID:8050369^[10]	IMP: Inferred from Mutant Phenotype	WB:WBVar00051372	P	From WB
	GO:0051259	protein oligomerization	WB_REF:WBPaper00001358 PMID:2175254^[2]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P10085	P	From WB
	GO:0051291	protein heterooligomerization	WB_REF:WBPaper00001358 PMID:2175254^[2]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P10085	P	From WB
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Lehner B et al. (2006) Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat Genet 38: 896-903 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Krause M et al. (1990) CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis. Cell 63: 907-19 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Lei H et al. (2009) Caudal-like PAL-1 directly activates the bodywall muscle module regulator hlh-1 in C. elegans to initiate the embryonic muscle gene regulatory network. Development 136: 1241-9 PubMed GONUTS page
↑ Grove CA et al. (2009) A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138: 314-27 PubMed GONUTS page
↑ Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
↑ ^6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 ^6.13 ^6.14 ^6.15 Baugh LR et al. (2005) Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. Genome Biol 6: R45 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Tischler J et al. (2006) Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution. Genome Biol 7: R69 PubMed GONUTS page
↑ Timmons L et al. (2001) Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263: 103-12 PubMed GONUTS page
↑ ^9.0 ^9.1 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
↑ Chen L et al. (1994) The Caenorhabditis elegans MYOD homologue HLH-1 is essential for proper muscle function and complete morphogenesis. Development 120: 1631-41 PubMed GONUTS page

[PMID:16845399-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Lehner B et al. (2006) Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat Genet 38: 896-903 PubMed GONUTS page

[PMID:2175254-1] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Krause M et al. (1990) CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis. Cell 63: 907-19 PubMed GONUTS page

[PMID:19261701-2] 3.0 ^3.1 ^3.2 Lei H et al. (2009) Caudal-like PAL-1 directly activates the bodywall muscle module regulator hlh-1 in C. elegans to initiate the embryonic muscle gene regulatory network. Development 136: 1241-9 PubMed GONUTS page

[PMID:19632181-3] Grove CA et al. (2009) A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138: 314-27 PubMed GONUTS page

[PMID:15791247-4] Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page

[PMID:15892873-5] 6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 ^6.13 ^6.14 ^6.15 Baugh LR et al. (2005) Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. Genome Biol 6: R45 PubMed GONUTS page

[PMID:16884526-6] 7.0 ^7.1 ^7.2 ^7.3 Tischler J et al. (2006) Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution. Genome Biol 7: R69 PubMed GONUTS page

[PMID:11223248-7] Timmons L et al. (2001) Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263: 103-12 PubMed GONUTS page

[PMID:14551910-8] 9.0 ^9.1 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page

[PMID:8050369-9] Chen L et al. (1994) The Caenorhabditis elegans MYOD homologue HLH-1 is essential for proper muscle function and complete morphogenesis. Development 120: 1631-41 PubMed GONUTS page

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Species (Taxon ID)	Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s)	hlh-1 ( synonyms: B0304.1 )
Protein Name(s)	No Information Provided.
External Links
WB	WBGene00001948

WB:hlh-1

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