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WB:ego-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) ego-1 ( synonyms: F26A3.3, ego-6 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00001214

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00027756
PMID:16845399[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064617
WB:WBPhenotype:0000688

P

From WB

GO:0000794

condensed nuclear chromosome

WB_REF:WBPaper00035270
PMID:19804758[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0000910

cytokinesis

WB_REF:WBPaper00004402
PMID:11099033[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00000033
WB:WBPhenotype:0001018

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00027756
PMID:16845399[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064710
WB:WBPhenotype:0000054

P

From WB

GO:0003968

RNA-directed RNA polymerase activity

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR007855

F

From WB

GO:0005634

nucleus

WB_REF:WBPaper00026940
PMID:16271877[6]

IDA: Inferred from Direct Assay

C

From WB

GO:0005634

nucleus

WB_REF:WBPaper00035270
PMID:19804758[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00035270
PMID:19804758[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0007186

G-protein coupled receptor signaling pathway

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000276

P

From WB

GO:0007276

gamete generation

WB_REF:WBPaper00035270
PMID:19804758[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00082034
WB:WBPhenotype:0000684

P

From WB

GO:0007281

germ cell development

WB_REF:WBPaper00002279
PMID:8647392[7]

IGI: Inferred from Genetic Interaction

WB:WBGene00001609

P

From WB

GO:0007283

spermatogenesis

WB_REF:WBPaper00004137
PMID:10704412[8]

IMP: Inferred from Mutant Phenotype

WB:WBVar00094610
WB:WBVar00094616
WB:WBVar00094622

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004402
PMID:11099033[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00000033
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00025240
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00045589
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00027756
PMID:16845399[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064710
WB:WBPhenotype:0000050

P

From WB

GO:0010171

body morphogenesis

WB_REF:WBPaper00027756
PMID:16845399[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064710
WB:WBPhenotype:0000535

P

From WB

GO:0016021

integral to membrane

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000276

C

From WB

GO:0016246

RNA interference

WB_REF:WBPaper00004137
PMID:10704412[8]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0031081

nuclear pore distribution

WB_REF:WBPaper00025208
PMID:15911573[11]

IMP: Inferred from Mutant Phenotype

WB:WBVar00094620

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00004402
PMID:11099033[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00000033
WB:WBPhenotype:0000031

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00027756
PMID:16845399[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064710
WB:WBPhenotype:0000031

P

From WB

GO:0043186

P granule

WB_REF:WBPaper00035270
PMID:19804758[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0048477

oogenesis

WB_REF:WBPaper00004137
PMID:10704412[8]

IMP: Inferred from Mutant Phenotype

WB:WBVar00094610
WB:WBVar00094616
WB:WBVar00094622

P

From WB

GO:0070090

metaphase plate

WB_REF:WBPaper00035270
PMID:19804758[2]

IDA: Inferred from Direct Assay

C

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Lehner B et al. (2006) Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat Genet 38: 896-903 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Claycomb JM et al. (2009) The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 139: 123-34 PubMed GONUTS page
  3. 3.0 3.1 3.2 Fraser AG et al. (2000) Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408: 325-30 PubMed GONUTS page
  4. 4.0 4.1 4.2 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  5. 5.0 5.1 5.2 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  6. Maine EM et al. (2005) EGO-1, a putative RNA-dependent RNA polymerase, is required for heterochromatin assembly on unpaired dna during C. elegans meiosis. Curr Biol 15: 1972-8 PubMed GONUTS page
  7. Qiao L et al. (1995) Enhancers of glp-1, a gene required for cell-signaling in Caenorhabditis elegans, define a set of genes required for germline development. Genetics 141: 551-69 PubMed GONUTS page
  8. 8.0 8.1 8.2 Smardon A et al. (2000) EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans. Curr Biol 10: 169-78 PubMed GONUTS page
  9. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  10. Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  11. Vought VE et al. (2005) EGO-1, a putative RNA-directed RNA polymerase, promotes germline proliferation in parallel with GLP-1/notch signaling and regulates the spatial organization of nuclear pore complexes and germline P granules in Caenorhabditis elegans. Genetics 170: 1121-32 PubMed GONUTS page
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