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WB:dpy-18

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) dpy-18 ( synonyms: Y47D3B.10, phy-1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00001077

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004656

procollagen-proline 4-dioxygenase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013547

F

From WB

GO:0005506

iron ion binding

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006620

F

From WB

GO:0005623

cell

WB_REF:WBPaper00003394
PMID:9952163[3]

IDA: Inferred from Direct Assay

C

From WB

GO:0005783

endoplasmic reticulum

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013547

C

From WB

GO:0005783

endoplasmic reticulum

WB_REF:WBPaper00005422
PMID:12036960[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0009790

embryo development

WB_REF:WBPaper00003994
PMID:10805750[5]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0010171

body morphogenesis

WB_REF:WBPaper00006395
PMID:14551910[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026722
WB:WBPhenotype:0000583

P

From WB

GO:0010172

embryonic body morphogenesis

WB_REF:WBPaper00039988
PMID:21795395[7]

IGI: Inferred from Genetic Interaction

WB:WBGene00006498

P

From WB

GO:0016491

oxidoreductase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005123

F

From WB

GO:0016702

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013547

F

From WB

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006620

F

From WB

GO:0016706

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005123

F

From WB

GO:0031418

L-ascorbic acid binding

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006620

F

From WB

GO:0031545

peptidyl-proline 4-dioxygenase activity

WB_REF:WBPaper00005678
PMID:12417582[8]

IDA: Inferred from Direct Assay

F

From WB

GO:0040002

collagen and cuticulin-based cuticle development

WB_REF:WBPaper00003994
PMID:10805750[5]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00005654
PMID:12529635[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009344
WB:WBPhenotype:0000643

P

From WB

GO:0040018

positive regulation of multicellular organism growth

WB_REF:WBPaper00005654
PMID:12529635[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009344
WB:WBPhenotype:0000229

P

From WB

GO:0040018

positive regulation of multicellular organism growth

WB_REF:WBPaper00029198
PMID:17374156[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00013352

P

From WB

GO:0043412

macromolecule modification

WB_REF:WBPaper00005678
PMID:12417582[8]

IDA: Inferred from Direct Assay

P

From WB

GO:0055114

oxidation-reduction process

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005123

P

From WB

GO:0055114

oxidation-reduction process

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006620

P

From WB

GO:0055114

oxidation-reduction process

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013547

P

From WB

GO:0055114

oxidation-reduction process

WB_REF:WBPaper00005678
PMID:12417582[8]

IDA: Inferred from Direct Assay

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  3. Kayser EB et al. (1999) GAS-1: a mitochondrial protein controls sensitivity to volatile anesthetics in the nematode Caenorhabditis elegans. Anesthesiology 90: 545-54 PubMed GONUTS page
  4. Myllyharju J et al. (2002) The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits. J Biol Chem 277: 29187-96 PubMed GONUTS page
  5. 5.0 5.1 Winter AD & Page AP (2000) Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans. Mol Cell Biol 20: 4084-93 PubMed GONUTS page
  6. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  7. Topf U & Chiquet-Ehrismann R (2011) Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV-mediated basement membrane integrity during late elongation of the embryo. Mol Biol Cell 22: 3331-43 PubMed GONUTS page
  8. 8.0 8.1 8.2 Winter AD et al. (2003) A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase. J Biol Chem 278: 2554-62 PubMed GONUTS page
  9. 9.0 9.1 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  10. Soete G et al. (2007) Regulation of Caenorhabditis elegans body size and male tail development by the novel gene lon-8. BMC Dev Biol 7: 20 PubMed GONUTS page
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