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WB:dat-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) dat-1 ( synonyms: T23G5.5 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00000934

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005254

chloride channel activity

WB_REF:WBPaper00024866
PMID:15520385[1]

IDA: Inferred from Direct Assay

F

From WB

GO:0005275

amine transmembrane transporter activity

WB_REF:WBPaper00005147
PMID:11867711[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091482

F

From WB

GO:0005328

neurotransmitter:sodium symporter activity

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000175

F

From WB

GO:0005330

dopamine:sodium symporter activity

WB_REF:WBPaper00003230
PMID:9765501[5]

IDA: Inferred from Direct Assay

F

From WB

GO:0005330

dopamine:sodium symporter activity

WB_REF:WBPaper00024866
PMID:15520385[1]

IDA: Inferred from Direct Assay

F

From WB

GO:0006821

chloride transport

WB_REF:WBPaper00024866
PMID:15520385[1]

IDA: Inferred from Direct Assay

P

From WB

GO:0006836

neurotransmitter transport

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000175

P

From WB

GO:0015837

amine transport

WB_REF:WBPaper00005147
PMID:11867711[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00091482

P

From WB

GO:0016021

integral to membrane

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

CBS:TMHMM

C

From WB

GO:0016021

integral to membrane

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000175

C

From WB

GO:0042734

presynaptic membrane

WB_REF:WBPaper00031346
PMID:18094261[6]

IDA: Inferred from Direct Assay

C

From WB

GO:0051583

dopamine uptake

WB_REF:WBPaper00003230
PMID:9765501[5]

IDA: Inferred from Direct Assay

P

From WB

GO:0051583

dopamine uptake

WB_REF:WBPaper00024866
PMID:15520385[1]

IDA: Inferred from Direct Assay

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Carvelli L et al. (2004) Dopamine transporters depolarize neurons by a channel mechanism. Proc Natl Acad Sci U S A 101: 16046-51 PubMed GONUTS page
  2. 2.0 2.1 Nass R et al. (2002) Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans. Proc Natl Acad Sci U S A 99: 3264-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  5. 5.0 5.1 Jayanthi LD et al. (1998) The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter. Mol Pharmacol 54: 601-9 PubMed GONUTS page
  6. McDonald PW et al. (2007) Vigorous motor activity in Caenorhabditis elegans requires efficient clearance of dopamine mediated by synaptic localization of the dopamine transporter DAT-1. J Neurosci 27: 14216-27 PubMed GONUTS page
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