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WB:daf-18

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) daf-18 ( synonyms: T07A9.6 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00000913

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002009

morphogenesis of an epithelium

WB_REF:WBPaper00005599
PMID:12445391[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008024
WB:WBPhenotype:0000038

P

From WB

GO:0004725

protein tyrosine phosphatase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000242

F

From WB

GO:0004725

protein tyrosine phosphatase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR016130

F

From WB

GO:0004725

protein tyrosine phosphatase activity

WB_REF:WBPaper00035407
PMID:19853560[4]

IMP: Inferred from Mutant Phenotype

F

From WB

GO:0005634

nucleus

WB_REF:WBPaper00035407
PMID:19853560[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0005886

plasma membrane

WB_REF:WBPaper00035407
PMID:19853560[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0006470

protein dephosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000242

P

From WB

GO:0006470

protein dephosphorylation

WB_REF:WBPaper00035407
PMID:19853560[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0007611

learning or memory

WB_REF:WBPaper00028460
PMID:16950159[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088917
WB:WBVar00143952

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00004702
PMID:11381260[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00000912

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00032946
PMID:19249087[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00079094
WB:WBPhenotype:0001171

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00037741
PMID:21040400[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084951
WB:WBPhenotype:0001171

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00037741
PMID:21040400[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084954
WB:WBPhenotype:0001171

P

From WB

GO:0009408

response to heat

WB_REF:WBPaper00004702
PMID:11381260[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00000912

P

From WB

GO:0009898

internal side of plasma membrane

WB_REF:WBPaper00028460
PMID:16950159[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0016311

dephosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR016130

P

From WB

GO:0016791

phosphatase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR016130

F

From WB

GO:0030424

axon

WB_REF:WBPaper00028460
PMID:16950159[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0030425

dendrite

WB_REF:WBPaper00028460
PMID:16950159[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00032946
PMID:19249087[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00079099
WB:WBPhenotype:0000031

P

From WB

GO:0040024

dauer larval development

WB_REF:WBPaper00004702
PMID:11381260[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00000912

P

From WB

GO:0042992

negative regulation of transcription factor import into nucleus

WB_REF:WBPaper00004702
PMID:11381260[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00000912

P

From WB

GO:0043025

neuronal cell body

WB_REF:WBPaper00028460
PMID:16950159[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0050920

regulation of chemotaxis

WB_REF:WBPaper00028460
PMID:16950159[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088917
WB:WBVar00143952

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Piano F et al. (2002) Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr Biol 12: 1959-64 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Brisbin S et al. (2009) A role for C. elegans Eph RTK signaling in PTEN regulation. Dev Cell 17: 459-69 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Tomioka M et al. (2006) The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans. Neuron 51: 613-25 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Lin K et al. (2001) Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet 28: 139-45 PubMed GONUTS page
  7. 7.0 7.1 Padmanabhan S et al. (2009) A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation. Cell 136: 939-51 PubMed GONUTS page
  8. 8.0 8.1 Mouchiroud L et al. (2011) Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans. Aging Cell 10: 39-54 PubMed GONUTS page
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