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WB:ced-12

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) ced-12 ( synonyms: Y106G6E.5, mig-16 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00000426

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005856

cytoskeleton

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006816

C

From WB

GO:0005886

plasma membrane

WB_REF:WBPaper00004897
PMID:11595183[3]

IDA: Inferred from Direct Assay

C

From WB

GO:0006909

phagocytosis

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006816

P

From WB

GO:0007015

actin filament organization

WB_REF:WBPaper00005200
PMID:11703939[4]

IDA: Inferred from Direct Assay

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00004897
PMID:11595183[3]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0017124

SH3 domain binding

WB_REF:WBPaper00004899
PMID:11703940[5]

TAS: Traceable Author Statement

F

From WB

GO:0030334

regulation of cell migration

WB_REF:WBPaper00006309
PMID:14688791[6]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088205

P

From WB

GO:0035262

gonad morphogenesis

WB_REF:WBPaper00006309
PMID:14688791[6]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088205

P

From WB

GO:0043652

engulfment of apoptotic cell

WB_REF:WBPaper00005200
PMID:11703939[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0044444

cytoplasmic part

WB_REF:WBPaper00005200
PMID:11703939[4]

IDA: Inferred from Direct Assay

C

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  2. 2.0 2.1 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  3. 3.0 3.1 Gumienny TL et al. (2001) CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell 107: 27-41 PubMed GONUTS page
  4. 4.0 4.1 4.2 Zhou Z et al. (2001) The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev Cell 1: 477-89 PubMed GONUTS page
  5. Wu YC et al. (2001) C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment. Dev Cell 1: 491-502 PubMed GONUTS page
  6. 6.0 6.1 Nishiwaki K et al. (2004) An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans. Nat Cell Biol 6: 31-7 PubMed GONUTS page
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