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WB:atg-18

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) atg-18 ( synonyms: F41E6.13, atgr-18 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00018294

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002119

nematode larval development

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073088
WB:WBPhenotype:0000059

P

From WB

GO:0006914

autophagy

WB_REF:WBPaper00006070
PMID:12958363[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000898

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00040180
PMID:21906946[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00001609

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00027160
PMID:16530747[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065173
WB:WBPhenotype:0000050

P

From WB

GO:0010314

phosphatidylinositol-5-phosphate binding

WB_REF:WBPaper00039980
PMID:21802374[5]

IDA: Inferred from Direct Assay

F

From WB

GO:0012501

programmed cell death

WB_REF:WBPaper00031045
PMID:17901876[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00000950

P

From WB

GO:0012501

programmed cell death

WB_REF:WBPaper00031045
PMID:17901876[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00003168

P

From WB

GO:0030163

protein catabolic process

WB_REF:WBPaper00028912
PMID:17172799[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0032266

phosphatidylinositol-3-phosphate binding

WB_REF:WBPaper00039980
PMID:21802374[5]

IDA: Inferred from Direct Assay

F

From WB

GO:0040007

growth

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073088
WB:WBPhenotype:0000059

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00006395
PMID:14551910[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00027330
WB:WBPhenotype:0000031

P

From WB

GO:0040024

dauer larval development

WB_REF:WBPaper00006070
PMID:12958363[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000898

P

From WB

GO:0043277

apoptotic cell clearance

WB_REF:WBPaper00037958
PMID:21183797[9]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0048598

embryonic morphogenesis

WB_REF:WBPaper00038090
PMID:21285529[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00000418

P

From WB

GO:0061365

positive regulation of triglyceride lipase activity

WB_REF:WBPaper00040180
PMID:21906946[3]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0070265

necrotic cell death

WB_REF:WBPaper00031045
PMID:17901876[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086905
WB:WBPhenotype:0000415

P

From WB

GO:0070265

necrotic cell death

WB_REF:WBPaper00031045
PMID:17901876[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086906
WB:WBPhenotype:0000415

P

From WB

GO:0070265

necrotic cell death

WB_REF:WBPaper00031045
PMID:17901876[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086907
WB:WBPhenotype:0000415

P

From WB

GO:0070273

phosphatidylinositol-4-phosphate binding

WB_REF:WBPaper00039980
PMID:21802374[5]

IDA: Inferred from Direct Assay

F

From WB

GO:0080025

phosphatidylinositol-3,5-bisphosphate binding

WB_REF:WBPaper00039980
PMID:21802374[5]

IDA: Inferred from Direct Assay

F

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ceron J et al. (2007) Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. BMC Dev Biol 7: 30 PubMed GONUTS page
  2. 2.0 2.1 Meléndez A et al. (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301: 1387-91 PubMed GONUTS page
  3. 3.0 3.1 Lapierre LR et al. (2011) Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr Biol 21: 1507-14 PubMed GONUTS page
  4. Schaheen L et al. (2006) Basis of lethality in C. elegans lacking CUP-5, the Mucolipidosis Type IV orthologue. Dev Biol 293: 382-91 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Lu Q et al. (2011) The WD40 repeat PtdIns(3)P-binding protein EPG-6 regulates progression of omegasomes to autophagosomes. Dev Cell 21: 343-57 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Samara C et al. (2008) Autophagy is required for necrotic cell death in Caenorhabditis elegans. Cell Death Differ 15: 105-12 PubMed GONUTS page
  7. Jia K et al. (2007) Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans. Autophagy 3: 21-5 PubMed GONUTS page
  8. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  9. Ruck A et al. (2011) The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans. Autophagy 7: 386-400 PubMed GONUTS page
  10. Borsos E et al. (2011) Autophagy and apoptosis are redundantly required for C. elegans embryogenesis. Autophagy 7: 557-9 PubMed GONUTS page
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