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WB:akt-1
Contents |
| Species (Taxon ID) | Caenorhabditis elegans (nematode) (taxon:6239) | |
| Gene Name(s) | akt-1 ( synonyms: C12D8.10, akt-1b ) | |
| Protein Name(s) | No Information Provided. | |
| External Links | ||
| WB | WBGene00000102 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000719 |
F |
From WB |
|||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR001245 |
F |
From WB |
|||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002290 |
F |
From WB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000961 |
F |
From WB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR008271 |
F |
From WB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017892 |
F |
From WB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
WB_REF:WBPaper00003173 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From WB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
WB_REF:WBPaper00031617 |
IDA: Inferred from Direct Assay |
F |
From WB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020635 |
F |
From WB |
|||
| GO:0005516 |
calmodulin binding |
WB_REF:WBPaper00030800 |
IDA: Inferred from Direct Assay |
F |
From WB |
|||
| GO:0005516 |
calmodulin binding |
WB_REF:WBPaper00031011 |
IPI: Inferred from Physical Interaction |
F |
From WB |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000719 |
F |
From WB |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000961 |
F |
From WB |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002290 |
F |
From WB |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017441 |
F |
From WB |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017892 |
F |
From WB |
|||
| GO:0005543 |
phospholipid binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR001849 |
F |
From WB |
|||
| GO:0005622 |
intracellular |
WB_REF:WBPaper00003173 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000719 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR000961 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR001245 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002290 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR008271 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017892 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020635 |
P |
From WB |
|||
| GO:0006468 |
protein phosphorylation |
WB_REF:WBPaper00003173 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From WB |
|||
| GO:0008286 |
insulin receptor signaling pathway |
WB_REF:WBPaper00003173 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00003872 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00013413 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00038561 |
P |
From WB |
||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00013413 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00038564 |
P |
From WB |
||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00026643 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00065303 |
P |
From WB |
||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00031617 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00087412 |
P |
From WB |
||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00031617 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00087414 |
P |
From WB |
||
| GO:0008340 |
determination of adult lifespan |
WB_REF:WBPaper00031617 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00087415 |
P |
From WB |
||
| GO:0043053 |
dauer entry |
WB_REF:WBPaper00013413 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00038561 |
P |
From WB |
||
| GO:0043053 |
dauer entry |
WB_REF:WBPaper00013413 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00038563 |
P |
From WB |
||
| GO:0043053 |
dauer entry |
WB_REF:WBPaper00013413 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00038564 |
P |
From WB |
||
| GO:0043053 |
dauer entry |
WB_REF:WBPaper00013413 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00038566 |
P |
From WB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Paradis S & Ruvkun G (1998) Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes Dev 12: 2488-98 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Tullet JM et al. (2008) Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132: 1025-38 PubMed GONUTS page
- ↑ Dong B et al. (2007) Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1. J Biol Chem 282: 25131-40 PubMed GONUTS page
- ↑ Shen X et al. (2008) Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome. Cell Calcium 43: 444-56 PubMed GONUTS page
- ↑ Vanfleteren JR & Braeckman BP (1999) Mechanisms of life span determination in Caenorhabditis elegans. Neurobiol Aging 20: 487-502 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 Hertweck M et al. (2004) C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Dev Cell 6: 577-88 PubMed GONUTS page
- ↑ Hamilton B et al. (2005) A systematic RNAi screen for longevity genes in C. elegans. Genes Dev 19: 1544-55 PubMed GONUTS page