WB:T19E10.1b

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Annotations

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes
	GO:0000003	reproduction	WB:WBPaper00005654 PMID:12529635^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00009185 WB:WBPhenotype:0000689	P	From WB
	GO:0000003	reproduction	WB:WBPaper00024497 PMID:15489339^[2]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00035675 WB:WBPhenotype:0000689	P	From WB
	GO:0000003	reproduction	WB:WBPaper00026774 PMID:16170304^[3]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064007 WB:WBPhenotype:0000688	P	From WB
	GO:0000910	cytokinesis	WB:WBPaper00025054 PMID:15791247^[4]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00053550 WB:WBPhenotype:0001018	P	From WB
	GO:0000910	cytokinesis	WB:WBPaper00026774 PMID:16170304^[3]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064008 WB:WBPhenotype:0001018	P	From WB
	GO:0000910	cytokinesis	WB:WBPaper00026774 PMID:16170304^[3]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064010 WB:WBPhenotype:0001018	P	From WB
	GO:0000910	cytokinesis	WB:WBPaper00031005 PMID:17848508^[5]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0002009	morphogenesis of an epithelium	WB:WBPaper00005654 PMID:12529635^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00009185 WB:WBPhenotype:0000038	P	From WB
	GO:0002119	nematode larval development	WB:WBPaper00024497 PMID:15489339^[2]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00035675 WB:WBPhenotype:0000054	P	From WB
	GO:0005089	Rho guanyl-nucleotide exchange factor activity	PMID:12520011^[6] PMID:12654719^[7]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR000219	F	From WB
	GO:0005622	intracellular	PMID:12520011^[6] PMID:12654719^[7]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR000219	C	From WB
	GO:0005622	intracellular	PMID:12520011^[6] PMID:12654719^[7]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR001357	C	From WB
	GO:0005938	cell cortex	WB:WBPaper00028408 PMID:16921365^[8]	IDA: Inferred from Direct Assay		C	From WB
	GO:0006898	receptor-mediated endocytosis	WB:WBPaper00030951 PMID:17704769^[9]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00071217 WB:WBPhenotype:0001425	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB:WBPaper00005654 PMID:12529635^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00009185 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB:WBPaper00006395 PMID:14551910^[10]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00026318 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB:WBPaper00025054 PMID:15791247^[4]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00053550 WB:WBPhenotype:0000050	P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB:WBPaper00028408 PMID:16921365^[8]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00065656 WB:WBPhenotype:0000050	P	From WB
	GO:0016477	cell migration	WB:WBPaper00026774 PMID:16170304^[3]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064008 WB:WBPhenotype:0000594	P	From WB
	GO:0016477	cell migration	WB:WBPaper00026774 PMID:16170304^[3]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064010 WB:WBPhenotype:0000594	P	From WB
	GO:0032880	regulation of protein localization	WB:WBPaper00027197 PMID:16580995^[11]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0032970	regulation of actin filament-based process	WB:WBPaper00031005 PMID:17848508^[5]	IGI: Inferred from Genetic Interaction	WB:WBGene00019600 WB:WBGene00022286	P	From WB
	GO:0032970	regulation of actin filament-based process	WB:WBPaper00031005 PMID:17848508^[5]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0035023	regulation of Rho protein signal transduction	PMID:12520011^[6] PMID:12654719^[7]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR000219	P	From WB
	GO:0040002	collagen and cuticulin-based cuticle development	WB:WBPaper00024497 PMID:15489339^[2]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00035675 WB:WBPhenotype:0000025	P	From WB
	GO:0040011	locomotion	WB:WBPaper00026774 PMID:16170304^[3]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00064007 WB:WBPhenotype:0000643	P	From WB
	GO:0040015	negative regulation of multicellular organism growth	WB:WBPaper00024497 PMID:15489339^[2]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00035675 WB:WBPhenotype:0000022	P	From WB
	GO:0040017	positive regulation of locomotion	WB:WBPaper00005654 PMID:12529635^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00009185 WB:WBPhenotype:0000646	P	From WB
	GO:0040035	hermaphrodite genitalia development	WB:WBPaper00005654 PMID:12529635^[1]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00009185 WB:WBPhenotype:0000697	P	From WB
	GO:0045167	asymmetric protein localization involved in cell fate determination	WB:WBPaper00031005 PMID:17848508^[5]	IMP: Inferred from Mutant Phenotype		P	From WB
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Rual JF et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-8 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Morita K et al. (2005) The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells. EMBO Rep 6: 1163-8 PubMed GONUTS page
↑ ^4.0 ^4.1 Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Schonegg S et al. (2007) The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos. Proc Natl Acad Sci U S A 104: 14976-81 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
↑ ^8.0 ^8.1 Motegi F & Sugimoto A (2006) Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos. Nat Cell Biol 8: 978-85 PubMed GONUTS page
↑ Balklava Z et al. (2007) Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nat Cell Biol 9: 1066-73 PubMed GONUTS page
↑ Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
↑ Motegi F et al. (2006) Two phases of astral microtubule activity during cytokinesis in C. elegans embryos. Dev Cell 10: 509-20 PubMed GONUTS page

{{{LINEAGE}}}

[PMID:12529635-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page

[PMID:15489339-1] 2.0 ^2.1 ^2.2 ^2.3 Rual JF et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-8 PubMed GONUTS page

[PMID:16170304-2] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Morita K et al. (2005) The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells. EMBO Rep 6: 1163-8 PubMed GONUTS page

[PMID:15791247-3] 4.0 ^4.1 Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page

[PMID:17848508-4] 5.0 ^5.1 ^5.2 ^5.3 Schonegg S et al. (2007) The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos. Proc Natl Acad Sci U S A 104: 14976-81 PubMed GONUTS page

[PMID:12520011-5] 6.0 ^6.1 ^6.2 ^6.3 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page

[PMID:12654719-6] 7.0 ^7.1 ^7.2 ^7.3 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page

[PMID:16921365-7] 8.0 ^8.1 Motegi F & Sugimoto A (2006) Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos. Nat Cell Biol 8: 978-85 PubMed GONUTS page

[PMID:17704769-8] Balklava Z et al. (2007) Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nat Cell Biol 9: 1066-73 PubMed GONUTS page

[PMID:14551910-9] Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page

[PMID:16580995-10] Motegi F et al. (2006) Two phases of astral microtubule activity during cytokinesis in C. elegans embryos. Dev Cell 10: 509-20 PubMed GONUTS page

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Species (Taxon ID)	Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s)	T19E10.1b ( synonyms: T19E10.1, let-21 )
Protein Name(s)	No Information Provided.
External Links
WB	WBGene00002297

WB:T19E10.1b

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