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VIBCH:Q9ZH73

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Contents

Species (Taxon ID) Vibrio cholerae. ([1])
Gene Name(s) varA
Protein Name(s) GacA-like protein
External Links
EMBL AF071105
HSSP Q56312
ProteinModelPortal Q9ZH73
GO GO:0005622
GO:0043565
GO:0003700
GO:0000156
InterPro IPR011006
IPR016032
IPR001789
IPR000792
IPR011991
Gene3D G3DSA:1.10.10.10
Pfam PF00196
PF00072
PRINTS PR00038
SMART SM00421
SM00448
SUPFAM SSF46894
SSF52172
PROSITE PS00622
PS50043
PS50110

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000156

two-component response regulator activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789

F

Seeded From UniProt

GO:0000156

two-component response regulator activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016032

F

Seeded From UniProt

GO:0000160

two-component signal transduction system (phosphorelay)

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789

P

Seeded From UniProt

GO:0000160

two-component signal transduction system (phosphorelay)

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016032

P

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016032

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded From UniProt

GO:0003700

sequence-specific DNA binding transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

F

Seeded From UniProt

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

C

Seeded From UniProt

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016032

C

Seeded From UniProt

GO:0006351

transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016032

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

Seeded From UniProt

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000792

F

Seeded From UniProt

GO:0009405

pathogenesis

PMID:9826365[1]

IMP: Inferred from Mutant Phenotype

P

Table 2 shows the varA deficient mutant has reduced expression of cholera toxin when compared to wild type, and varA mutant reverted to wild type.

Additionally, Table 4 shows that varA mutants have a lower competitive index in mice colonization.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wong SM et al. (1998) Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators. Infect Immun 66: 5854-61 PubMed GONUTS page
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