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TAIR:MPK4

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Contents

Species (Taxon ID) Arabidopsis thaliana (thale cress) (taxon:3702)
Gene Name(s) MPK4 ( synonyms: AT4G01370, ATMPK4, MPK4, MAP kinase 4, F2N1.1, F2N1_1, AT4G01370.1 )
Protein Name(s) AT4G01370, MAP kinase 4,
External Links
TAIR locus:2124943

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000165

MAPK cascade

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003527
INTERPRO:IPR008351

P

From TAIR

GO:0004672

protein kinase activity

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719
INTERPRO:IPR002290

F

From TAIR

GO:0004674

protein serine/threonine kinase activity

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008271

F

From TAIR

GO:0004707

MAP kinase activity

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003527
INTERPRO:IPR008351

F

From TAIR

GO:0004707

MAP kinase activity

TAIR:Publication:5002
PMID:8282107[1]

ISS: Inferred from Sequence or Structural Similarity

F

From TAIR

GO:0004707

MAP kinase activity

TAIR:Publication:5002
PMID:8282107[1]

ISS: Inferred from Sequence or Structural Similarity

Pfam:PF00069

F

From TAIR

GO:0004707

MAP kinase activity

TAIR:Publication:501683496
PMID:12119167[2]

ISS: Inferred from Sequence or Structural Similarity

Pfam:PF00069

F

From TAIR

GO:0004707

MAP kinase activity

TAIR:Publication:501716337
PMID:15990873[3]

IDA: Inferred from Direct Assay

F

From TAIR

GO:0004713

protein tyrosine kinase activity

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501712959
PMID:15225555[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q94A06

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501712959
PMID:15225555[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q9S7U9

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501716337
PMID:15990873[3]

IPI: Inferred from Physical Interaction

UniProtKB:O22921

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501733362
PMID:19513235[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q94A06

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501733362
PMID:19513235[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q9S7U9

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501736474
PMID:20215588[6]

IPI: Inferred from Physical Interaction

UniProtKB:Q9FLP0

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501741439
PMID:21203436[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q8LGD5

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501743366
PMID:21798944[8]

IPI: Inferred from Physical Interaction

UniProtKB:Q8LGD5

F

From TAIR

GO:0005524

ATP binding

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719
INTERPRO:IPR002290
INTERPRO:IPR003527
INTERPRO:IPR008351
INTERPRO:IPR017441

F

From TAIR

GO:0005634

nucleus

TAIR:Publication:501714452
PMID:15610358[9]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005634

nucleus

TAIR:Publication:501716337
PMID:15990873[3]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005737

cytoplasm

TAIR:Publication:501716337
PMID:15990873[3]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005829

cytosol

TAIR:Publication:501741191
PMID:21166475[10]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0006468

protein phosphorylation

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719
INTERPRO:IPR002290
INTERPRO:IPR003527
INTERPRO:IPR008271
INTERPRO:IPR008351
INTERPRO:IPR020635

P

From TAIR

GO:0006950

response to stress

TAIR:Publication:501683496
PMID:12119167[2]

TAS: Traceable Author Statement

P

From TAIR

GO:0006972

hyperosmotic response

TAIR:Publication:501713222
PMID:15358537[11]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0007112

male meiosis cytokinesis

TAIR:Publication:501742734
PMID:21575092[12]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0007165

signal transduction

TAIR:Publication:501683496
PMID:12119167[2]

IC: Inferred by Curator

GO:0004707

P

From TAIR

GO:0009409

response to cold

TAIR:Publication:501712959
PMID:15225555[4]

IDA: Inferred from Direct Assay

P

From TAIR

GO:0009555

pollen development

TAIR:Publication:501742734
PMID:21575092[12]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009607

response to biotic stimulus

TAIR:Publication:1345949
PMID:11123804[13]

TAS: Traceable Author Statement

P

From TAIR

GO:0009620

response to fungus

TAIR:Publication:501719292
PMID:16813576[14]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009651

response to salt stress

TAIR:Publication:501712959
PMID:15225555[4]

IDA: Inferred from Direct Assay

P

From TAIR

GO:0009737

response to abscisic acid stimulus

TAIR:Publication:501724221
PMID:18248592[15]

IEP: Inferred from Expression Pattern

P

From TAIR

GO:0009861

jasmonic acid and ethylene-dependent systemic resistance

TAIR:Publication:501719292
PMID:16813576[14]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009862

systemic acquired resistance, salicylic acid mediated signaling pathway

TAIR:Publication:501683496
PMID:12119167[2]

TAS: Traceable Author Statement

P

From TAIR

GO:0009862

systemic acquired resistance, salicylic acid mediated signaling pathway

TAIR:Publication:501719292
PMID:16813576[14]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009868

jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway

TAIR:Publication:501680501
PMID:11544109[16]

TAS: Traceable Author Statement

P

From TAIR

GO:0016301

kinase activity

TAIR:Communication:501714663

ISS: Inferred from Sequence or Structural Similarity

Pfam:PF00069

F

From TAIR

GO:0016310

phosphorylation

TAIR:Publication:501716337
PMID:15990873[3]

IDA: Inferred from Direct Assay

P

From TAIR

GO:0016772

transferase activity, transferring phosphorus-containing groups

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR011009

F

From TAIR

GO:0023014

signal transduction by phosphorylation

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003527
INTERPRO:IPR008351

P

From TAIR

GO:0042539

hypotonic salinity response

TAIR:Publication:501713222
PMID:15358537[11]

IDA: Inferred from Direct Assay

P

From TAIR

GO:0043622

cortical microtubule organization

TAIR:Publication:501736474
PMID:20215588[6]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0043622

cortical microtubule organization

TAIR:Publication:501736474
PMID:20215588[6]

IMP: Inferred from Mutant Phenotype

UniProtKB:Q39024

P

From TAIR


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Mizoguchi T et al. (1993) ATMPKs: a gene family of plant MAP kinases in Arabidopsis thaliana. FEBS Lett 336: 440-4 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 (2002) Mitogen-activated protein kinase cascades in plants: a new nomenclature. Trends Plant Sci 7: 301-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Andreasson E et al. (2005) The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO J 24: 2579-89 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Teige M et al. (2004) The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis. Mol Cell 15: 141-52 PubMed GONUTS page
  5. 5.0 5.1 Lee JS et al. (2008) Comprehensive analysis of protein-protein interactions between Arabidopsis MAPKs and MAPK kinases helps define potential MAPK signalling modules. Plant Signal Behav 3: 1037-41 PubMed GONUTS page
  6. 6.0 6.1 6.2 Beck M et al. (2010) Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization. Plant Cell 22: 755-71 PubMed GONUTS page
  7. Petersen K et al. (2010) Arabidopsis MKS1 is involved in basal immunity and requires an intact N-terminal domain for proper function. PLoS One 5: e14364 PubMed GONUTS page
  8. (2011) Evidence for network evolution in an Arabidopsis interactome map. Science 333: 601-7 PubMed GONUTS page
  9. Koroleva OA et al. (2005) High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Plant J 41: 162-74 PubMed GONUTS page
  10. Ito J et al. (2011) Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. J Proteome Res 10: 1571-82 PubMed GONUTS page
  11. 11.0 11.1 Droillard MJ et al. (2004) Involvement of MPK4 in osmotic stress response pathways in cell suspensions and plantlets of Arabidopsis thaliana: activation by hypoosmolarity and negative role in hyperosmolarity tolerance. FEBS Lett 574: 42-8 PubMed GONUTS page
  12. 12.0 12.1 Zeng Q et al. (2011) AtMPK4 is required for male-specific meiotic cytokinesis in Arabidopsis. Plant J 67: 895-906 PubMed GONUTS page
  13. Ichimura K et al. (2000) Various abiotic stresses rapidly activate Arabidopsis MAP kinases ATMPK4 and ATMPK6. Plant J 24: 655-65 PubMed GONUTS page
  14. 14.0 14.1 14.2 Brodersen P et al. (2006) Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4. Plant J 47: 532-46 PubMed GONUTS page
  15. Xing Y et al. (2008) AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis. Plant J 54: 440-51 PubMed GONUTS page
  16. Innes RW (2001) Mapping out the roles of MAP kinases in plant defense. Trends Plant Sci 6: 392-4 PubMed GONUTS page
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