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TAIR:GP ALPHA 1

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Contents

Species (Taxon ID) Arabidopsis thaliana (thale cress) (taxon:3702)
Gene Name(s) GP ALPHA 1 ( synonyms: AT2G26300, GPA1, GP ALPHA 1, ATGPA1, G PROTEIN ALPHA SUBUNIT 1, ARABIDOPSIS THALIANA G PROTEIN ALPHA SUBUNIT 1, t1d16.6, t1d16_6, G PROTEIN ALPHA SUBUNIT, AT2G26300.1 )
Protein Name(s) AT2G26300, G protein alpha subunit 1,
External Links
TAIR locus:2005529

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001664

G-protein coupled receptor binding

TAIR:Communication:501741973

PANTHER:PTHR10218_AN0

F

From TAIR

GO:0001789

G-protein signaling, coupled to S1P second messenger (sphingosine kinase activating)

TAIR:Publication:501707013
PMID:12789341[1]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0003924

GTPase activity

TAIR:Publication:501710519
PMID:14500984[2]

IDA: Inferred from Direct Assay

F

From TAIR

GO:0003924

GTPase activity

TAIR:Publication:501713033
PMID:15313574[3]

IDA: Inferred from Direct Assay

F

From TAIR

GO:0003924

GTPase activity

TAIR:Publication:501723319
PMID:17951432[4]

IDA: Inferred from Direct Assay

F

From TAIR

GO:0004871

signal transducer activity

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001019
INTERPRO:IPR002976
INTERPRO:IPR011025

F

From TAIR

GO:0004871

signal transducer activity

TAIR:Communication:501714663

ISS: Inferred from Sequence or Structural Similarity

INTERPRO:IPR001019

F

From TAIR

GO:0004871

signal transducer activity

TAIR:Communication:501741973

PANTHER:PTHR10218_AN0

F

From TAIR

GO:0005095

GTPase inhibitor activity

TAIR:Publication:501730286
PMID:19135895[5]

IDA: Inferred from Direct Assay

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501707745
PMID:12837948[6]

IPI: Inferred from Physical Interaction

UniProtKB:Q9LX49

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501711495
PMID:14594812[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q38882

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501712420
PMID:15155892[8]

IPI: Inferred from Physical Interaction

UniProtKB:O04714

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501718987
PMID:16582010[9]

IPI: Inferred from Physical Interaction

UniProtKB:Q9SKT0

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501721123
PMID:17347412[10]

IPI: Inferred from Physical Interaction

UniProtKB:O04714

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501721123
PMID:17347412[10]

IPI: Inferred from Physical Interaction

UniProtKB:Q9C929

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501723319
PMID:17951432[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q8H1F2

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501730286
PMID:19135895[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q0WQG8

F

From TAIR

GO:0005515

protein binding

TAIR:Publication:501730286
PMID:19135895[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q9XIP7

F

From TAIR

GO:0005525

GTP binding

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002976

F

From TAIR

GO:0005525

GTP binding

TAIR:Publication:501723319
PMID:17951432[4]

IDA: Inferred from Direct Assay

F

From TAIR

GO:0005789

endoplasmic reticulum membrane

TAIR:Publication:3248
PMID:9175885[11]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005834

heterotrimeric G-protein complex

TAIR:Publication:1345954
PMID:11121078[12]

IPI: Inferred from Physical Interaction

C

From TAIR

GO:0005834

heterotrimeric G-protein complex

TAIR:Publication:501714697
PMID:15705948[13]

TAS: Traceable Author Statement

C

From TAIR

GO:0005886

plasma membrane

TAIR:Publication:3248
PMID:9175885[11]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005886

plasma membrane

TAIR:Publication:501710519
PMID:14500984[2]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005886

plasma membrane

TAIR:Publication:501718909
PMID:16618929[14]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005886

plasma membrane

TAIR:Publication:501720929
PMID:17317660[15]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0005886

plasma membrane

TAIR:Publication:501722708
PMID:17644812[16]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0006471

protein ADP-ribosylation

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002976

P

From TAIR

GO:0006571

tyrosine biosynthetic process

TAIR:Publication:501718375
PMID:16415218[17]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0007165

signal transduction

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR011025

P

From TAIR

GO:0007186

G-protein coupled receptor signaling pathway

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001019
INTERPRO:IPR002976

P

From TAIR

GO:0007186

G-protein coupled receptor signaling pathway

TAIR:Communication:501714663

ISS: Inferred from Sequence or Structural Similarity

INTERPRO:IPR001019

P

From TAIR

GO:0007188

G-protein signaling, coupled to cAMP nucleotide second messenger

TAIR:Communication:501741973

PANTHER:PTHR10218_AN0

P

From TAIR

GO:0008219

cell death

TAIR:Publication:501714697
PMID:15705948[13]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009094

L-phenylalanine biosynthetic process

TAIR:Publication:501718375
PMID:16415218[17]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009506

plasmodesma

TAIR:Publication:501742898
PMID:21533090[18]

IDA: Inferred from Direct Assay

C

From TAIR

GO:0009738

abscisic acid mediated signaling pathway

TAIR:Publication:501680768
PMID:11408655[19]

TAS: Traceable Author Statement

P

From TAIR

GO:0009738

abscisic acid mediated signaling pathway

TAIR:Publication:501720908
PMID:17322342[20]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009740

gibberellic acid mediated signaling pathway

TAIR:Publication:501681533
PMID:12068128[21]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009749

response to glucose stimulus

TAIR:Publication:501723319
PMID:17951432[4]

IGI: Inferred from Genetic Interaction

AGI_LocusCode:AT3G26090

P

From TAIR

GO:0009785

blue light signaling pathway

TAIR:Publication:501720908
PMID:17322342[20]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009788

negative regulation of abscisic acid mediated signaling pathway

TAIR:Publication:501718994
PMID:16581874[22]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009789

positive regulation of abscisic acid mediated signaling pathway

TAIR:Publication:501718926
PMID:16614222[23]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009845

seed germination

TAIR:Publication:501681533
PMID:12068128[21]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0009845

seed germination

TAIR:Publication:501718994
PMID:16581874[22]

IEP: Inferred from Expression Pattern

P

From TAIR

GO:0010027

thylakoid membrane organization

TAIR:Publication:501729814
PMID:19228339[24]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0010119

regulation of stomatal movement

TAIR:Publication:501714697
PMID:15705948[13]

TAS: Traceable Author Statement

P

From TAIR

GO:0010119

regulation of stomatal movement

TAIR:Publication:501718926
PMID:16614222[23]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0010244

response to low fluence blue light stimulus by blue low-fluence system

TAIR:Publication:501718375
PMID:16415218[17]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0016247

channel regulator activity

TAIR:Publication:501680768
PMID:11408655[19]

IMP: Inferred from Mutant Phenotype

F

From TAIR

GO:0019001

guanyl nucleotide binding

TAIR:AnalysisReference:501748310

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001019

F

From TAIR

GO:0031234

extrinsic to internal side of plasma membrane

TAIR:Communication:501741973

PANTHER:PTHR10218_AN0

C

From TAIR

GO:0031683

G-protein beta/gamma-subunit complex binding

TAIR:Communication:501741973

PANTHER:PTHR10218_AN0

F

From TAIR

GO:0042127

regulation of cell proliferation

TAIR:Publication:501710519
PMID:14500984[2]

IMP: Inferred from Mutant Phenotype

P

From TAIR

GO:0051020

GTPase binding

TAIR:Publication:501730286
PMID:19135895[5]

IPI: Inferred from Physical Interaction

F

From TAIR

GO:0071215

cellular response to abscisic acid stimulus

TAIR:Publication:501718994
PMID:16581874[22]

IEP: Inferred from Expression Pattern

P

From TAIR

GO:0072593

reactive oxygen species metabolic process

TAIR:Publication:501714697
PMID:15705948[13]

IMP: Inferred from Mutant Phenotype

P

From TAIR


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Coursol S et al. (2003) Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins. Nature 423: 651-4 PubMed GONUTS page
  2. 2.0 2.1 2.2 Chen JG et al. (2003) A seven-transmembrane RGS protein that modulates plant cell proliferation. Science 301: 1728-31 PubMed GONUTS page
  3. Willard FS & Siderovski DP (2004) Purification and in vitro functional analysis of the Arabidopsis thaliana regulator of G-protein signaling-1. Methods Enzymol 389: 320-38 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Johnston CA et al. (2007) GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling. Proc Natl Acad Sci U S A 104: 17317-22 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Pandey S et al. (2009) Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis. Cell 136: 136-48 PubMed GONUTS page
  6. Lapik YR & Kaufman LS (2003) The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development. Plant Cell 15: 1578-90 PubMed GONUTS page
  7. Zhao J & Wang X (2004) Arabidopsis phospholipase Dalpha1 interacts with the heterotrimeric G-protein alpha-subunit through a motif analogous to the DRY motif in G-protein-coupled receptors. J Biol Chem 279: 1794-800 PubMed GONUTS page
  8. Pandey S & Assmann SM (2004) The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling. Plant Cell 16: 1616-32 PubMed GONUTS page
  9. Huang J et al. (2006) The plastid protein THYLAKOID FORMATION1 and the plasma membrane G-protein GPA1 interact in a novel sugar-signaling mechanism in Arabidopsis. Plant Cell 18: 1226-38 PubMed GONUTS page
  10. 10.0 10.1 Liu X et al. (2007) A G protein-coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid. Science 315: 1712-6 PubMed GONUTS page
  11. 11.0 11.1 Weiss CA et al. (1997) The G protein alpha subunit (GP alpha1) is associated with the ER and the plasma membrane in meristematic cells of Arabidopsis and cauliflower. FEBS Lett 407: 361-7 PubMed GONUTS page
  12. Mason MG & Botella JR (2000) Completing the heterotrimer: isolation and characterization of an Arabidopsis thaliana G protein gamma-subunit cDNA. Proc Natl Acad Sci U S A 97: 14784-8 PubMed GONUTS page
  13. 13.0 13.1 13.2 13.3 Joo JH et al. (2005) Different signaling and cell death roles of heterotrimeric G protein alpha and beta subunits in the Arabidopsis oxidative stress response to ozone. Plant Cell 17: 957-70 PubMed GONUTS page
  14. Dunkley TP et al. (2006) Mapping the Arabidopsis organelle proteome. Proc Natl Acad Sci U S A 103: 6518-23 PubMed GONUTS page
  15. Benschop JJ et al. (2007) Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. Mol Cell Proteomics 6: 1198-214 PubMed GONUTS page
  16. Marmagne A et al. (2007) A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Mol Cell Proteomics 6: 1980-96 PubMed GONUTS page
  17. 17.0 17.1 17.2 Warpeha KM et al. (2006) G-protein-coupled receptor 1, G-protein Galpha-subunit 1, and prephenate dehydratase 1 are required for blue light-induced production of phenylalanine in etiolated Arabidopsis. Plant Physiol 140: 844-55 PubMed GONUTS page
  18. Fernandez-Calvino L et al. (2011) Arabidopsis plasmodesmal proteome. PLoS One 6: e18880 PubMed GONUTS page
  19. 19.0 19.1 Wang XQ et al. (2001) G protein regulation of ion channels and abscisic acid signaling in Arabidopsis guard cells. Science 292: 2070-2 PubMed GONUTS page
  20. 20.0 20.1 Warpeha KM et al. (2007) The GCR1, GPA1, PRN1, NF-Y signal chain mediates both blue light and abscisic acid responses in Arabidopsis. Plant Physiol 143: 1590-600 PubMed GONUTS page
  21. 21.0 21.1 Ullah H et al. (2002) Role of a heterotrimeric G protein in regulation of Arabidopsis seed germination. Plant Physiol 129: 897-907 PubMed GONUTS page
  22. 22.0 22.1 22.2 Pandey S et al. (2006) G-protein complex mutants are hypersensitive to abscisic acid regulation of germination and postgermination development. Plant Physiol 141: 243-56 PubMed GONUTS page
  23. 23.0 23.1 Mishra G et al. (2006) A bifurcating pathway directs abscisic acid effects on stomatal closure and opening in Arabidopsis. Science 312: 264-6 PubMed GONUTS page
  24. Zhang L et al. (2009) Activation of the heterotrimeric G protein alpha-subunit GPA1 suppresses the ftsh-mediated inhibition of chloroplast development in Arabidopsis. Plant J 58: 1041-53 PubMed GONUTS page
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