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STRCO:RELA

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Contents

Species (Taxon ID) Streptomyces coelicolor. ([1])
Gene Name(s) relA
Protein Name(s) GTP pyrophosphokinase

(p)ppGpp synthase ATP:GTP 3'-pyrophosphotransferase ppGpp synthase I

External Links
EMBL X87267
X92520
AL939109
PIR S70687
RefSeq NP_625792.1
ProteinModelPortal P52560
GeneID 1096939
GenomeReviews AL645882_GR
KEGG sco:SCO1513
NMPDR fig|100226.1.peg.1480
HOGENOM HBG594146
OMA HRGQKRK
ProtClustDB CLSK812689
GO GO:0016597
GO:0005524
GO:0005525
GO:0008728
GO:0016301
GO:0046872
GO:0008081
GO:0015969
GO:0006950
InterPro IPR002912
IPR012675
IPR003607
IPR006674
IPR007685
IPR004811
IPR004095
IPR012676
Gene3D G3DSA:3.10.20.30
PANTHER PTHR21262
Pfam PF01842
PF01966
PF04607
PF02824
SMART SM00471
SM00954
SUPFAM SSF81271
TIGRFAMs TIGR00691

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003607

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0342

F

Seeded From UniProt

GO:0006950

response to stress

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0346

P

Seeded From UniProt

GO:0008081

phosphoric diester hydrolase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006674

F

Seeded From UniProt

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002912

P

Seeded From UniProt

GO:0008728

GTP diphosphokinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.6.5

F

Seeded From UniProt

GO:0015969

guanosine tetraphosphate metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004811

P

Seeded From UniProt

GO:0015969

guanosine tetraphosphate metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007685

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

Seeded From UniProt

GO:0016597

amino acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002912

F

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006674

F

Seeded From UniProt

GO:0015970

guanosine tetraphosphate biosynthetic process

PMID:9294445[1]

IMP: Inferred from Mutant Phenotype

P

The levels of ppGpp in M600 7.5 and 15 min after amino acid depletion (223 and 347 pmol mg21[dry weight], respectively) were comparable to earlier estimates for relA+ S. coelicolor M145 (200 pmol mg 21 [dry weight]; 54) and J1929::KC301 (292 and 542 pmol mg 21 [dry weight] in duplicate experiments) and fell in the range observed for other Streptomyces species (56); in contrast, there was no detectable ppGpp in M570.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Chakraburtty R & Bibb M (1997) The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation. J Bacteriol 179: 5854-61 PubMed GONUTS page
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