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STRCO:PTHP

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Contents

Species (Taxon ID) Streptomyces coelicolor. ([1])
Gene Name(s) ptsH
Protein Name(s) Phosphocarrier protein HPr

Histidine-containing protein

External Links
EMBL AL939125
PIR T35877
RefSeq NP_629964.1
ProteinModelPortal O50515
PhosSite O50515
GeneID 1101283
GenomeReviews AL645882_GR
KEGG sco:SCO5841
NMPDR fig|100226.1.peg.5790
HOGENOM HBG653254
OMA WAEGLHA
ProtClustDB CLSK636212
GO GO:0005737
GO:0016301
GO:0005351
GO:0009401
InterPro IPR001020
IPR005698
IPR000032
Gene3D G3DSA:3.30.1340.10
Pfam PF00381
PRINTS PR00107
SUPFAM SSF55594
TIGRFAMs TIGR01003
PROSITE PS51350
PS00369

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005351

sugar:hydrogen symporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000032

F

Seeded From UniProt

GO:0005351

sugar:hydrogen symporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001020

F

Seeded From UniProt

GO:0005351

sugar:hydrogen symporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005698

F

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0006810

transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001020

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded From UniProt

GO:0008643

carbohydrate transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0762

P

Seeded From UniProt

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000032

P

Seeded From UniProt

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001020

P

Seeded From UniProt

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005698

P

Seeded From UniProt

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0598

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

PMID:12533468[1]

IMP: Inferred from Mutant Phenotype

P

Fig 1B and Table 1:

To investigate the role of HPr in vivo, the ptsH gene was inactivated by gene replacement with the apramycin resistance gene aacC4. The derived mutant was verified by Southern blotting and was designated BAP1 (ΔptsH::aacC4) (see Materials and Methods). Western blotting was performed to determine whether the ptsH gene product was absent.

BAP1 did not grow on fructose, while growth on glucose, mannitol, glycerol, glutamate, and other carbon sources tested was unchanged.

Phosphorylation of fructose was not detectable in extracts of BAP1 grown in the presence or absence of fructose.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Nothaft H et al. (2003) In vivo analysis of HPr reveals a fructose-specific phosphotransferase system that confers high-affinity uptake in Streptomyces coelicolor. J Bacteriol 185: 929-37 PubMed GONUTS page
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