STRCO:PTHP

Species (Taxon ID)	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145). (100226)
Gene Name(s)	ptsH
Protein Name(s)	Phosphocarrier protein HPr Histidine-containing protein
External Links
UniProt	O50515
EMBL	AL939125
PIR	T35877
RefSeq	NP_629964.1
ProteinModelPortal	O50515
STRING	100226.SCO5841
PhosSite	P010471
PRIDE	O50515
EnsemblBacteria	CAA15798
GeneID	1101283
KEGG	sco:SCO5841
PATRIC	23741582
eggNOG	NOG80964
HOGENOM	HOG000278398
InParanoid	O50515
KO	K11189
OMA	RRVNVGW
OrthoDB	EOG6XDGX2
PhylomeDB	O50515
Proteomes	UP000001973
GO	GO:0005737 GO:0004674 GO:0009401
Gene3D	3.30.1340.10
InterPro	IPR000032 IPR001020
Pfam	PF00381
PRINTS	PR00107
SUPFAM	SSF55594
TIGRFAMs	TIGR01003
PROSITE	PS51350 PS00369

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	PMID:12533468	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008643	carbohydrate transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0762	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0598	P		Seeded From UniProt	complete
	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	PMID:12533468	ECO:0000315			P		Fig 1B and Table 1: To investigate the role of HPr in vivo, the ptsH gene was inactivated by gene replacement with the apramycin resistance gene aacC4. The derived mutant was verified by Southern blotting and was designated BAP1 (ΔptsH::aacC4) (see Materials and Methods). Western blotting was performed to determine whether the ptsH gene product was absent. BAP1 did not grow on fructose, while growth on glucose, mannitol, glycerol, glutamate, and other carbon sources tested was unchanged. Phosphorylation of fructose was not detectable in extracts of BAP1 grown in the presence or absence of fructose.	complete CACAO 2597
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References

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