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STRCO:FABH3
Contents |
| Species (Taxon ID) | Streptomyces coelicolor. ([1]) | |
| Gene Name(s) | fabH3 | |
| Protein Name(s) | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 3
3-oxoacyl-[acyl-carrier-protein] synthase III protein 3 Beta-ketoacyl-ACP synthase III 3 KAS III 3 | |
| External Links | ||
| EMBL | AL939125 | |
| PIR | T34914 | |
| RefSeq | NP_630009.1 | |
| ProteinModelPortal | O54151 | |
| GeneID | 1101330 | |
| GenomeReviews | AL645882_GR | |
| KEGG | sco:SCO5888 | |
| NMPDR | fig|100226.1.peg.5837 | |
| HOGENOM | HBG649927 | |
| OMA | HTIFMEG | |
| ProtClustDB | PRK09352 | |
| GO | GO:0005737 GO:0004315 GO:0033818 GO:0006633 | |
| HAMAP | MF_01815 | |
| InterPro | IPR013751 IPR013747 IPR004655 IPR016039 IPR016038 | |
| Gene3D | G3DSA:3.40.47.10 | |
| Pfam | PF08545 PF08541 | |
| SUPFAM | SSF53901 | |
| TIGRFAMs | TIGR00747 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004315 |
3-oxoacyl-(acyl-carrier-protein) synthase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004315 |
3-oxoacyl-(acyl-carrier-protein) synthase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0006633 |
fatty acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006633 |
fatty acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006633 |
fatty acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008610 |
lipid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008610 |
lipid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016746 |
transferase activity, transferring acyl groups |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0033818 |
beta-ketoacyl-acyl-carrier-protein synthase III activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0033818 |
beta-ketoacyl-acyl-carrier-protein synthase III activity |
IMP: Inferred from Mutant Phenotype |
F |
..we have shown for the first time a replacement of FabH with a heterologous enzyme with only 35% of amino acid identity and dramatically different acyl-CoA substrate specificity. The resulting dramatic shift in the fatty acid profile provides the first unequivocal in vivo evidence that the observed substrate specificity of FabH determines the type of fatty acid product made by a type II FAS. Figure 3. Table 1. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Li Y et al. (2005) Alteration of the fatty acid profile of Streptomyces coelicolor by replacement of the initiation enzyme 3-ketoacyl acyl carrier protein synthase III (FabH). J Bacteriol 187: 3795-9 PubMed GONUTS page
3bc |
flmt |
t cont. |
