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STAAC:PFLA

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Contents

Species (Taxon ID) Staphylococcus aureus (strain COL). (taxon:93062)
Gene Name(s) pflA
Protein Name(s)
  • Pyruvate formate-lyase-activating enzyme
  • PFL-activating enzyme
External Links
UniProt Identifier PFLA_STAAC
UniProt Accessions Q5HJF3,
EMBL CP000046,
RefSeq YP_185104.1,
Pfam PF04055,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0055114

oxidation-reduction process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

GO:0051536

iron-sulfur cluster binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0411

F

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012838

P

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

F

GO:0043365

(formate-C-acetyltransferase)-activating enzyme activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012838

F

GO:0043365

(formate-C-acetyltransferase)-activating enzyme activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.97.1.4

F

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

P

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0004

F

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

GO:0006006

glucose metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0313

P

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

GO:0006800

oxygen and reactive oxygen species metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

P

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

F

GO:0005975

carbohydrate metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0119

P

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007197

F

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0016491

oxidoreductase activity

PMID:21169491[1]

IMP: Inferred from Mutant Phenotype

F

FIG. 2. Formate accumulation in the TSB culture supernatant of anaerobically grown cells. TABLE 4. Accumulated fermentation products, glucose consumption, pH of culture supernatant, and OD578 after anaerobic growth in IMDMa

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007197

F

GO:0015943

formate biosynthetic process

PMID:21169491[1]

IMP: Inferred from Mutant Phenotype

P

FIG. 4. Glucose consumption and formate accumulation in culture supernatants as detected by 1H-NMR.

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007197

F

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0005975

carbohydrate metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0119

P

GO:0006006

glucose metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0313

P

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

F

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

GO:0043365

(formate-C-acetyltransferase)-activating enzyme activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012838

F

GO:0043365

(formate-C-acetyltransferase)-activating enzyme activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.97.1.4

F

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007197

F

GO:0051536

iron-sulfur cluster binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0411

F

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

F

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0004

F

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001989

P

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012838

P

GO:0055114

oxidation-reduction process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Leibig M et al. (2011) Pyruvate formate lyase acts as a formate supplier for metabolic processes during anaerobiosis in Staphylococcus aureus. J Bacteriol 193: 952-62 PubMed GONUTS page
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