GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:YTA12
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | YTA12 ( synonyms: YMR089C, RCA1 ) | |
| Protein Name(s) | Component of the mitochondrial inner membrane m-AAA protease, | |
| External Links | ||
| SGD | S000004695 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0004222 |
metalloendopeptidase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005515 |
protein binding |
SGD_REF:S000134962 |
IPI: Inferred from Physical Interaction |
SGD:S000000819 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000134962 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000069459 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000069459 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000075100 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000117178 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0496 |
C |
From SGD |
||
| GO:0005743 |
mitochondrial inner membrane |
SGD_REF:S000039413 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005745 |
m-AAA complex |
SGD_REF:S000055187 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006461 |
protein complex assembly |
SGD_REF:S000055187 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006465 |
signal peptide processing |
SGD_REF:S000071826 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006508 |
proteolysis |
SGD_REF:S000055187 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006508 |
proteolysis |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006508 |
proteolysis |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
P |
From SGD |
||
| GO:0008233 |
peptidase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
F |
From SGD |
||
| GO:0008237 |
metallopeptidase activity |
SGD_REF:S000055187 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0008237 |
metallopeptidase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0482 |
F |
From SGD |
||
| GO:0008270 |
zinc ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016021 |
integral to membrane |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From SGD |
||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0016887 |
ATPase activity |
SGD_REF:S000039413 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0016887 |
ATPase activity |
SGD_REF:S000134962 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0016887 |
ATPase activity |
SGD_REF:S000134962 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0017111 |
nucleoside-triphosphatase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0030163 |
protein catabolic process |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0031966 |
mitochondrial membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0171 |
C |
From SGD |
||
| GO:0045041 |
protein import into mitochondrial intermembrane space |
SGD_REF:S000071826 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0097002 |
mitochondrial inner boundary membrane |
SGD_REF:S000128411 |
IDA: Inferred from Direct Assay |
C |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Augustin S et al. (2009) An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell 35: 574-85 PubMed GONUTS page
- ↑ 2.0 2.1 Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
- ↑ Sickmann A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100: 13207-12 PubMed GONUTS page
- ↑ Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
- ↑ 5.0 5.1 Tzagoloff A et al. (1994) A new member of a family of ATPases is essential for assembly of mitochondrial respiratory chain and ATP synthetase complexes in Saccharomyces cerevisiae. J Biol Chem 269: 26144-51 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Arlt H et al. (1996) The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell 85: 875-85 PubMed GONUTS page
- ↑ 7.0 7.1 Esser K et al. (2002) A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. J Mol Biol 323: 835-43 PubMed GONUTS page
- ↑ Suppanz IE et al. (2009) The m-AAA protease processes cytochrome c peroxidase preferentially at the inner boundary membrane of mitochondria. Mol Biol Cell 20: 572-80 PubMed GONUTS page
