GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:YPT1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | YPT1 ( synonyms: YFL038C, YP2 ) | |
| Protein Name(s) | Rab family GTPase, | |
| External Links | ||
| SGD | S000001856 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000139 |
Golgi membrane |
SGD_REF:S000050496 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0000139 |
Golgi membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0134 |
C |
From SGD |
||
| GO:0000149 |
SNARE binding |
SGD_REF:S000125992 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0000149 |
SNARE binding |
SGD_REF:S000125992 |
IPI: Inferred from Physical Interaction |
SGD:S000005601 |
F |
From SGD |
||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0000407 |
pre-autophagosomal structure |
SGD_REF:S000134404 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0003924 |
GTPase activity |
SGD_REF:S000045726 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003924 |
GTPase activity |
SGD_REF:S000065786 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005525 |
GTP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005525 |
GTP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0342 |
F |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0086 |
C |
From SGD |
||
| GO:0005739 |
mitochondrion |
SGD_REF:S000075100 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000117178 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005783 |
endoplasmic reticulum |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From SGD |
||
| GO:0005789 |
endoplasmic reticulum membrane |
SGD_REF:S000050496 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0097 |
C |
From SGD |
||
| GO:0005794 |
Golgi apparatus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0333 |
C |
From SGD |
||
| GO:0005795 |
Golgi stack |
SGD_REF:S000073252 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005802 |
trans-Golgi network |
SGD_REF:S000132797 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006461 |
protein complex assembly |
SGD_REF:S000052788 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006810 |
transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From SGD |
||
| GO:0006888 |
ER to Golgi vesicle-mediated transport |
SGD_REF:S000050361 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006888 |
ER to Golgi vesicle-mediated transport |
SGD_REF:S000057388 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006888 |
ER to Golgi vesicle-mediated transport |
SGD_REF:S000080776 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006890 |
retrograde vesicle-mediated transport, Golgi to ER |
SGD_REF:S000125992 |
IGI: Inferred from Genetic Interaction |
SGD:S000002597 |
P |
From SGD |
||
| GO:0006890 |
retrograde vesicle-mediated transport, Golgi to ER |
SGD_REF:S000125992 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0015031 |
protein transport |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0015031 |
protein transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016192 |
vesicle-mediated transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0931 |
P |
From SGD |
||
| GO:0016236 |
macroautophagy |
SGD_REF:S000134404 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0032258 |
CVT pathway |
SGD_REF:S000134404 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0032456 |
endocytic recycling |
SGD_REF:S000132797 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0034498 |
early endosome to Golgi transport |
SGD_REF:S000132797 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0035494 |
SNARE complex disassembly |
SGD_REF:S000056203 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0048194 |
Golgi vesicle budding |
SGD_REF:S000125992 |
IGI: Inferred from Genetic Interaction |
SGD:S000002597 |
P |
From SGD |
||
| GO:0048211 |
Golgi vesicle docking |
SGD_REF:S000050702 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0090114 |
COPII-coated vesicle budding |
SGD_REF:S000080776 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cao X & Barlowe C (2000) Asymmetric requirements for a Rab GTPase and SNARE proteins in fusion of COPII vesicles with acceptor membranes. J Cell Biol 149: 55-66 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Kamena F et al. (2008) Ypt1p is essential for retrograde Golgi-ER transport and for Golgi maintenance in S. cerevisiae. J Cell Sci 121: 1293-302 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Lynch-Day MA et al. (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A 107: 7811-6 PubMed GONUTS page
- ↑ Wagner P et al. (1987) Biochemical properties of the ras-related YPT protein in yeast: a mutational analysis. EMBO J 6: 2373-9 PubMed GONUTS page
- ↑ Richardson CJ et al. (1998) GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport. Mol Cell Biol 18: 827-38 PubMed GONUTS page
- ↑ Sickmann A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100: 13207-12 PubMed GONUTS page
- ↑ Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
- ↑ Calero M et al. (2003) Dual prenylation is required for Rab protein localization and function. Mol Biol Cell 14: 1852-67 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Sclafani A et al. (2010) Establishing a role for the GTPase Ypt1p at the late Golgi. Traffic 11: 520-32 PubMed GONUTS page
- ↑ Sapperstein SK et al. (1996) Assembly of the ER to Golgi SNARE complex requires Uso1p. J Cell Biol 132: 755-67 PubMed GONUTS page
- ↑ Bacon RA et al. (1989) The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J Cell Biol 109: 1015-22 PubMed GONUTS page
- ↑ Jedd G et al. (1995) The Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway. J Cell Biol 131: 583-90 PubMed GONUTS page
- ↑ 13.0 13.1 Ballew N et al. (2005) A Rab requirement is not bypassed in SLY1-20 suppression. Mol Biol Cell 16: 1839-49 PubMed GONUTS page
- ↑ Lupashin VV & Waters MG (1997) t-SNARE activation through transient interaction with a rab-like guanosine triphosphatase. Science 276: 1255-8 PubMed GONUTS page
- ↑ Cao X et al. (1998) Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins. EMBO J 17: 2156-65 PubMed GONUTS page
