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SGD:YKU80
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | YKU80 ( synonyms: YMR106C, HDF2 ) | |
| Protein Name(s) | Subunit of the telomeric Ku complex (Yku70p-Yku80p), | |
| External Links | ||
| SGD | S000004712 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0000723 |
telomere maintenance |
SGD_REF:S000047753 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000724 |
double-strand break repair via homologous recombination |
SGD_REF:S000059175 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000781 |
chromosome, telomeric region |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0779 |
C |
From SGD |
||
| GO:0000781 |
chromosome, telomeric region |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0276 |
C |
From SGD |
||
| GO:0000790 |
nuclear chromatin |
SGD_REF:S000039233 |
TAS: Traceable Author Statement |
C |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000086738 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From SGD |
||
| GO:0003684 |
damaged DNA binding |
SGD_REF:S000039233 |
TAS: Traceable Author Statement |
F |
From SGD |
|||
| GO:0003723 |
RNA binding |
SGD_REF:S000074098 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004003 |
ATP-dependent DNA helicase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004386 |
helicase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0005694 |
chromosome |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0158 |
C |
From SGD |
||
| GO:0005724 |
nuclear telomeric heterochromatin |
SGD_REF:S000070058 |
TAS: Traceable Author Statement |
C |
From SGD |
|||
| GO:0005958 |
DNA-dependent protein kinase-DNA ligase 4 complex |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0006281 |
DNA repair |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From SGD |
||
| GO:0006303 |
double-strand break repair via nonhomologous end joining |
SGD_REF:S000051563 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006303 |
double-strand break repair via nonhomologous end joining |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006310 |
DNA recombination |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006310 |
DNA recombination |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0233 |
P |
From SGD |
||
| GO:0006333 |
chromatin assembly or disassembly |
SGD_REF:S000068980 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006342 |
chromatin silencing |
SGD_REF:S000047483 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006342 |
chromatin silencing |
SGD_REF:S000047483 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006974 |
response to DNA damage stimulus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From SGD |
||
| GO:0007535 |
donor selection |
SGD_REF:S000086738 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0007535 |
donor selection |
SGD_REF:S000086738 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0007535 |
donor selection |
SGD_REF:S000116839 |
IGI: Inferred from Genetic Interaction |
SGD:S000001393 |
P |
From SGD |
||
| GO:0007535 |
donor selection |
SGD_REF:S000116839 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0034502 |
protein localization to chromosome |
SGD_REF:S000127464 |
IGI: Inferred from Genetic Interaction |
SGD:S000001809 |
P |
From SGD |
||
| GO:0042162 |
telomeric DNA binding |
SGD_REF:S000123576 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0043564 |
Ku70:Ku80 complex |
SGD_REF:S000041209 |
IDA: Inferred from Direct Assay |
C |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Driller L et al. (2000) A short C-terminal domain of Yku70p is essential for telomere maintenance. J Biol Chem 275: 24921-7 PubMed GONUTS page
- ↑ Cervelli T & Galli A (2000) Effects of HDF1 (Ku70) and HDF2 (Ku80) on spontaneous and DNA damage-induced intrachromosomal recombination in Saccharomyces cerevisiae. Mol Gen Genet 264: 56-63 PubMed GONUTS page
- ↑ 3.0 3.1 Martin SG et al. (1999) Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97: 621-33 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Ruan C et al. (2005) The DNA repair protein yKu80 regulates the function of recombination enhancer during yeast mating type switching. Mol Cell Biol 25: 8476-85 PubMed GONUTS page
- ↑ Stellwagen AE et al. (2003) Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 17: 2384-95 PubMed GONUTS page
- ↑ Luo K et al. (2002) Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast. Genes Dev 16: 1528-39 PubMed GONUTS page
- ↑ Hegde V & Klein H (2000) Requirement for the SRS2 DNA helicase gene in non-homologous end joining in yeast. Nucleic Acids Res 28: 2779-83 PubMed GONUTS page
- ↑ Thrower DA & Bloom K (2001) Dicentric chromosome stretching during anaphase reveals roles of Sir2/Ku in chromatin compaction in budding yeast. Mol Biol Cell 12: 2800-12 PubMed GONUTS page
- ↑ 9.0 9.1 Boulton SJ & Jackson SP (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17: 1819-28 PubMed GONUTS page
- ↑ 10.0 10.1 Coïc E et al. (2006) Cell cycle-dependent regulation of Saccharomyces cerevisiae donor preference during mating-type switching by SBF (Swi4/Swi6) and Fkh1. Mol Cell Biol 26: 5470-80 PubMed GONUTS page
- ↑ Patterson EE & Fox CA (2008) The Ku complex in silencing the cryptic mating-type loci of Saccharomyces cerevisiae. Genetics 180: 771-83 PubMed GONUTS page
- ↑ Sabourin M et al. (2007) Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol Cell 27: 550-61 PubMed GONUTS page
- ↑ Milne GT et al. (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol 16: 4189-98 PubMed GONUTS page
