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SGD:YDJ1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | YDJ1 ( synonyms: YNL064C, HSP40, MAS5 ) | |
| Protein Name(s) | Type I HSP40 co-chaperone involved in regulating HSP90 and HSP70, | |
| External Links | ||
| SGD | S000005008 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001671 |
ATPase activator activity |
SGD_REF:S000045398 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0001671 |
ATPase activator activity |
SGD_REF:S000077458 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0086 |
C |
From SGD |
||
| GO:0005792 |
microsome |
SGD_REF:S000051244 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005829 |
cytosol |
SGD_REF:S000051244 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005829 |
cytosol |
SGD_REF:S000055246 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006457 |
protein folding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR008971 |
P |
From SGD |
||
| GO:0006458 |
'de novo' protein folding |
SGD_REF:S000048279 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006626 |
protein targeting to mitochondrion |
SGD_REF:S000050215 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006810 |
transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From SGD |
||
| GO:0006950 |
response to stress |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0346 |
P |
From SGD |
||
| GO:0009408 |
response to heat |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0015031 |
protein transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From SGD |
||
| GO:0030433 |
ER-associated protein catabolic process |
SGD_REF:S000077133 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0030433 |
ER-associated protein catabolic process |
SGD_REF:S000077458 |
IGI: Inferred from Genetic Interaction |
P |
From SGD |
|||
| GO:0030433 |
ER-associated protein catabolic process |
SGD_REF:S000077458 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0031072 |
heat shock protein binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001623 |
F |
From SGD |
||
| GO:0042026 |
protein refolding |
SGD_REF:S000048256 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0045047 |
protein targeting to ER |
SGD_REF:S000056529 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0048471 |
perinuclear region of cytoplasm |
SGD_REF:S000051244 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0198 |
C |
From SGD |
||
| GO:0051082 |
unfolded protein binding |
SGD_REF:S000065137 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0051082 |
unfolded protein binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002939 |
F |
From SGD |
||
| GO:0072380 |
TRC complex |
SGD_REF:S000136745 |
IDA: Inferred from Direct Assay |
C |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cyr DM et al. (1992) Regulation of Hsp70 function by a eukaryotic DnaJ homolog. J Biol Chem 267: 20927-31 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Youker RT et al. (2004) Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast. Mol Biol Cell 15: 4787-97 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Caplan AJ & Douglas MG (1991) Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein. J Cell Biol 114: 609-21 PubMed GONUTS page
- ↑ Cyr DM & Douglas MG (1994) Differential regulation of Hsp70 subfamilies by the eukaryotic DnaJ homologue YDJ1. J Biol Chem 269: 9798-804 PubMed GONUTS page
- ↑ Meacham GC et al. (1999) Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing. J Biol Chem 274: 34396-402 PubMed GONUTS page
- ↑ Atencio DP & Yaffe MP (1992) MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import. Mol Cell Biol 12: 283-91 PubMed GONUTS page
- ↑ Huyer G et al. (2004) Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein. J Biol Chem 279: 38369-78 PubMed GONUTS page
- ↑ Glover JR & Lindquist S (1998) Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell 94: 73-82 PubMed GONUTS page
- ↑ Caplan AJ et al. (1992) YDJ1p facilitates polypeptide translocation across different intracellular membranes by a conserved mechanism. Cell 71: 1143-55 PubMed GONUTS page
- ↑ Lu Z & Cyr DM (1998) Protein folding activity of Hsp70 is modified differentially by the hsp40 co-chaperones Sis1 and Ydj1. J Biol Chem 273: 27824-30 PubMed GONUTS page
- ↑ Wang F et al. (2010) A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum. Mol Cell 40: 159-71 PubMed GONUTS page
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