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SGD:YAP1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) YAP1 ( synonyms: YML007W, PAR1, SNQ3 )
Protein Name(s) bZIP transcription factor required for oxidative stress tolerance,
External Links
SGD S000004466

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000304

response to singlet oxygen

SGD_REF:S000117354
PMID:16862604[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003700

sequence-specific DNA binding transcription factor activity

SGD_REF:S000058433
PMID:11056165[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003700

sequence-specific DNA binding transcription factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011616
InterPro:IPR004827

F

From SGD

GO:0005634

nucleus

SGD_REF:S000054581
PMID:9130715[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000069459
PMID:11914276[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000072694
PMID:12582119[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000054581
PMID:9130715[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000069459
PMID:11914276[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000072694
PMID:12582119[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011616
InterPro:IPR004827

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0009408

response to heat

SGD_REF:S000050112
PMID:10809786[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0010038

response to metal ion

SGD_REF:S000046513
PMID:8360174[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0042493

response to drug

SGD_REF:S000080916
PMID:15713640[8]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR004827
InterPro:IPR011616

F

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000129025
PMID:19158363[9]

IDA: Inferred from Direct Assay

F

From SGD

GO:0043619

regulation of transcription from RNA polymerase II promoter in response to oxidative stress

SGD_REF:S000058433
PMID:11056165[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0046686

response to cadmium ion

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0105

P

From SGD

GO:0046983

protein dimerization activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011616

F

From SGD

GO:0061395

positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance

SGD_REF:S000080191
PMID:15575969[10]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Brombacher K et al. (2006) The role of Yap1p and Skn7p-mediated oxidative stress response in the defence of Saccharomyces cerevisiae against singlet oxygen. Yeast 23: 741-50 PubMed GONUTS page
  2. 2.0 2.1 Nguyên DT et al. (2001) Multiple Yap1p-binding sites mediate induction of the yeast major facilitator FLR1 gene in response to drugs, oxidants, and alkylating agents. J Biol Chem 276: 1138-45 PubMed GONUTS page
  3. 3.0 3.1 Kuge S et al. (1997) Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16: 1710-20 PubMed GONUTS page
  4. 4.0 4.1 Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
  5. 5.0 5.1 Wiatrowski HA & Carlson M (2003) Yap1 accumulates in the nucleus in response to carbon stress in Saccharomyces cerevisiae. Eukaryot Cell 2: 19-26 PubMed GONUTS page
  6. Sugiyama K et al. (2000) The Yap1p-dependent induction of glutathione synthesis in heat shock response of Saccharomyces cerevisiae. J Biol Chem 275: 15535-40 PubMed GONUTS page
  7. Wu A et al. (1993) Yeast bZip proteins mediate pleiotropic drug and metal resistance. J Biol Chem 268: 18850-8 PubMed GONUTS page
  8. Lucau-Danila A et al. (2005) Early expression of yeast genes affected by chemical stress. Mol Cell Biol 25: 1860-8 PubMed GONUTS page
  9. Zhu C et al. (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19: 556-66 PubMed GONUTS page
  10. Haugen AC et al. (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol 5: R95 PubMed GONUTS page
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