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SGD:VPS45
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | VPS45 ( synonyms: YGL095C, STT10, VPL28 ) | |
| Protein Name(s) | Protein of the Sec1p/Munc-18 family, | |
| External Links | ||
| SGD | S000003063 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000011 |
vacuole inheritance |
SGD_REF:S000056533 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000139 |
Golgi membrane |
SGD_REF:S000050447 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0000149 |
SNARE binding |
SGD_REF:S000120431 |
IPI: Inferred from Physical Interaction |
SGD:S000005378 |
F |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0086 |
C |
From SGD |
||
| GO:0005773 |
vacuole |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0926 |
C |
From SGD |
||
| GO:0005774 |
vacuolar membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0271 |
C |
From SGD |
||
| GO:0005829 |
cytosol |
SGD_REF:S000047466 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006623 |
protein targeting to vacuole |
SGD_REF:S000040935 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006810 |
transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From SGD |
||
| GO:0006895 |
Golgi to endosome transport |
SGD_REF:S000055492 |
IGI: Inferred from Genetic Interaction |
SGD:S000002731 |
P |
From SGD |
||
| GO:0006896 |
Golgi to vacuole transport |
SGD_REF:S000050447 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006904 |
vesicle docking involved in exocytosis |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0007033 |
vacuole organization |
SGD_REF:S000054176 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0007035 |
vacuolar acidification |
SGD_REF:S000040935 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0015031 |
protein transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016192 |
vesicle-mediated transport |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0019898 |
extrinsic to membrane |
SGD_REF:S000050447 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0031201 |
SNARE complex |
SGD_REF:S000049070 |
IPI: Inferred from Physical Interaction |
SGD:S000002876 |
C |
From SGD |
||
| GO:0032258 |
CVT pathway |
SGD_REF:S000053954 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0035543 |
positive regulation of SNARE complex assembly |
SGD_REF:S000061408 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0048210 |
Golgi vesicle fusion to target membrane |
SGD_REF:S000054176 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0051082 |
unfolded protein binding |
SGD_REF:S000061408 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0051082 |
unfolded protein binding |
SGD_REF:S000061408 |
IPI: Inferred from Physical Interaction |
SGD:S000005378 |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Raymond CK et al. (1992) Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol Biol Cell 3: 1389-402 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Piper RC et al. (1994) Yeast Vps45p is a Sec1p-like protein required for the consumption of vacuole-targeted, post-Golgi transport vesicles. Eur J Cell Biol 65: 305-18 PubMed GONUTS page
- ↑ Carpp LN et al. (2006) The Sec1p/Munc18 protein Vps45p binds its cognate SNARE proteins via two distinct modes. J Cell Biol 173: 927-36 PubMed GONUTS page
- ↑ Gerhardt B et al. (1998) The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J Biol Chem 273: 15818-29 PubMed GONUTS page
- ↑ 5.0 5.1 Yoshida S et al. (1995) STT10, a novel class-D VPS yeast gene required for osmotic integrity related to the PKC1/STT1 protein kinase pathway. Gene 160: 117-22 PubMed GONUTS page
- ↑ Webb GC et al. (1997) Genetic interactions between a pep7 mutation and the PEP12 and VPS45 genes: evidence for a novel SNARE component in transport between the Saccharomyces cerevisiae Golgi complex and endosome. Genetics 147: 467-78 PubMed GONUTS page
- ↑ 7.0 7.1 Bryant NJ et al. (1998) Traffic into the prevacuolar/endosomal compartment of Saccharomyces cerevisiae: a VPS45-dependent intracellular route and a VPS45-independent, endocytic route. Eur J Cell Biol 76: 43-52 PubMed GONUTS page
- ↑ Coe JG et al. (1999) A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae. Mol Biol Cell 10: 2407-23 PubMed GONUTS page
- ↑ Abeliovich H et al. (1999) Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p. EMBO J 18: 6005-16 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Bryant NJ & James DE (2001) Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation. EMBO J 20: 3380-8 PubMed GONUTS page
