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SGD:VAC8

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) VAC8 ( synonyms: YEL013W, YEB3 )
Protein Name(s) Phosphorylated and palmitoylated vacuolar membrane protein,
External Links
SGD S000000739

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000011

vacuole inheritance

SGD_REF:S000054952
PMID:8885233[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000011

vacuole inheritance

SGD_REF:S000113766
PMID:16301533[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000329

fungal-type vacuole membrane

SGD_REF:S000042692
PMID:9664035[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000329

fungal-type vacuole membrane

SGD_REF:S000046657
PMID:9739084[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000329

fungal-type vacuole membrane

SGD_REF:S000056230
PMID:9490720[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000329

fungal-type vacuole membrane

SGD_REF:S000113766
PMID:16301533[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005773

vacuole

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0926

C

From SGD

GO:0005774

vacuolar membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0271

C

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016236

macroautophagy

SGD_REF:S000081925
PMID:15901835[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0034727

piecemeal microautophagy of nucleus

SGD_REF:S000072498
PMID:12529432[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0034727

piecemeal microautophagy of nucleus

SGD_REF:S000127377
PMID:18701704[8]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0042144

vacuole fusion, non-autophagic

SGD_REF:S000065870
PMID:11441010[9]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0042144

vacuole fusion, non-autophagic

SGD_REF:S000113766
PMID:16301533[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0043495

protein anchor

SGD_REF:S000039257
PMID:10888680[10]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0043495

protein anchor

SGD_REF:S000039257
PMID:10888680[10]

IPI: Inferred from Physical Interaction

SGD:S000001238

F

From SGD

GO:0043495

protein anchor

SGD_REF:S000072665
PMID:12594460[11]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0043495

protein anchor

SGD_REF:S000072665
PMID:12594460[11]

IPI: Inferred from Physical Interaction

SGD:S000000568

F

From SGD

GO:0071255

CVT vesicle assembly

SGD_REF:S000054987
PMID:10837477[12]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0071561

nucleus-vacuole junction

SGD_REF:S000039257
PMID:10888680[10]

IDA: Inferred from Direct Assay

C

From SGD

GO:0071561

nucleus-vacuole junction

SGD_REF:S000039257
PMID:10888680[10]

IPI: Inferred from Physical Interaction

SGD:S000001238

C

From SGD

GO:0071562

nucleus-vacuole junction assembly

SGD_REF:S000039257
PMID:10888680[10]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0071563

Myo2p-Vac17p-Vac8p transport complex

SGD_REF:S000072498
PMID:12529432[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0071563

Myo2p-Vac17p-Vac8p transport complex

SGD_REF:S000072498
PMID:12529432[7]

IPI: Inferred from Physical Interaction

SGD:S000000568

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Wang YX et al. (1996) Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. Mol Biol Cell 7: 1375-89 PubMed GONUTS page
  2. 2.0 2.1 2.2 Hou H et al. (2005) The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8. Proc Natl Acad Sci U S A 102: 17366-71 PubMed GONUTS page
  3. Pan X & Goldfarb DS (1998) YEB3/VAC8 encodes a myristylated armadillo protein of the Saccharomyces cerevisiae vacuolar membrane that functions in vacuole fusion and inheritance. J Cell Sci 111 ( Pt 15): 2137-47 PubMed GONUTS page
  4. Fleckenstein D et al. (1998) Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha is associated with the yeast vacuole membrane. J Cell Sci 111 ( Pt 20): 3109-18 PubMed GONUTS page
  5. Wang YX et al. (1998) Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. J Cell Biol 140: 1063-74 PubMed GONUTS page
  6. Cheong H et al. (2005) Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell 16: 3438-53 PubMed GONUTS page
  7. 7.0 7.1 7.2 Roberts P et al. (2003) Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Mol Biol Cell 14: 129-41 PubMed GONUTS page
  8. Krick R et al. (2008) Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol Biol Cell 19: 4492-505 PubMed GONUTS page
  9. Wang YX et al. (2001) Fusion of docked membranes requires the armadillo repeat protein Vac8p. J Biol Chem 276: 35133-40 PubMed GONUTS page
  10. 10.0 10.1 10.2 10.3 10.4 Pan X et al. (2000) Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Mol Biol Cell 11: 2445-57 PubMed GONUTS page
  11. 11.0 11.1 Tang F et al. (2003) Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature 422: 87-92 PubMed GONUTS page
  12. Scott SV et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275: 25840-9 PubMed GONUTS page
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