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SGD:TUS1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) TUS1 ( synonyms: YLR425W, SOP10 )
Protein Name(s) Guanine nucleotide exchange factor (GEF) that modulate Rho1p activity,
External Links
SGD S000004417

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000131

incipient cellular bud site

SGD_REF:S000125436
PMID:18256282[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005083

small GTPase regulator activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001180

F

From SGD

GO:0005085

guanyl-nucleotide exchange factor activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

F

From SGD

GO:0005089

Rho guanyl-nucleotide exchange factor activity

SGD_REF:S000069495
PMID:11839800[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005089

Rho guanyl-nucleotide exchange factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

F

From SGD

GO:0005543

phospholipid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From SGD

GO:0005622

intracellular

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

C

From SGD

GO:0005935

cellular bud neck

SGD_REF:S000116305
PMID:16763112[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0007165

signal transduction

SGD_REF:S000069495
PMID:11839800[2]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0007165

signal transduction

SGD_REF:S000069495
PMID:11839800[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031505

fungal-type cell wall organization

SGD_REF:S000069495
PMID:11839800[2]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0031505

fungal-type cell wall organization

SGD_REF:S000069495
PMID:11839800[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0035023

regulation of Rho protein signal transduction

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Kono K et al. (2008) G1/S cyclin-dependent kinase regulates small GTPase Rho1p through phosphorylation of RhoGEF Tus1p in Saccharomyces cerevisiae. Mol Biol Cell 19: 1763-71 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Schmelzle T et al. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Mol Cell Biol 22: 1329-39 PubMed GONUTS page
  3. Yoshida S et al. (2006) Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis. Science 313: 108-11 PubMed GONUTS page
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