Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

SGD:TSC11

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) TSC11 ( synonyms: YER093C, AVO3 )
Protein Name(s) Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p),
External Links
SGD S000000895

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001558

regulation of cell growth

SGD_REF:S000071528
PMID:12408816[1]

IPI: Inferred from Physical Interaction

SGD:S000001686

P

From SGD

GO:0005085

guanyl-nucleotide exchange factor activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

F

From SGD

GO:0005515

protein binding

SGD_REF:S000072891
PMID:12631735[2]

IPI: Inferred from Physical Interaction

SGD:S000001686

F

From SGD

GO:0005624

membrane fraction

SGD_REF:S000122673
PMID:17507646[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005773

vacuole

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0926

C

From SGD

GO:0005774

vacuolar membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0271

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0030148

sphingolipid biosynthetic process

SGD_REF:S000055689
PMID:9804843[4]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0030950

establishment or maintenance of actin cytoskeleton polarity

SGD_REF:S000071528
PMID:12408816[1]

IPI: Inferred from Physical Interaction

SGD:S000001686

P

From SGD

GO:0030950

establishment or maintenance of actin cytoskeleton polarity

SGD_REF:S000081257
PMID:15809876[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031505

fungal-type cell wall organization

SGD_REF:S000081257
PMID:15809876[5]

IGI: Inferred from Genetic Interaction

SGD:S000000201

P

From SGD

GO:0031505

fungal-type cell wall organization

SGD_REF:S000081257
PMID:15809876[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031929

TOR signaling cascade

SGD_REF:S000071528
PMID:12408816[1]

IC: Inferred by Curator

GO:0031932

P

From SGD

GO:0031932

TORC2 complex

SGD_REF:S000071528
PMID:12408816[1]

IPI: Inferred from Physical Interaction

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Loewith R et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10: 457-68 PubMed GONUTS page
  2. Wedaman KP et al. (2003) Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14: 1204-20 PubMed GONUTS page
  3. Aronova S et al. (2007) Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae. Mol Biol Cell 18: 2779-94 PubMed GONUTS page
  4. Beeler T et al. (1998) The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant. J Biol Chem 273: 30688-94 PubMed GONUTS page
  5. 5.0 5.1 5.2 Ho HL et al. (2005) Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex. Curr Genet 47: 273-88 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox