GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:TOM1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | TOM1 ( synonyms: YDR457W ) | |
| Protein Name(s) | E3 ubiquitin ligase of the hect-domain class, | |
| External Links | ||
| SGD | S000002865 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000447 |
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
SGD_REF:S000060058 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000448 |
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
SGD_REF:S000060058 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000472 |
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
SGD_REF:S000060058 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000480 |
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
SGD_REF:S000060058 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000130860 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005622 |
intracellular |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000074185 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005730 |
nucleolus |
SGD_REF:S000074185 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005730 |
nucleolus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0188 |
C |
From SGD |
||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0006364 |
rRNA processing |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0698 |
P |
From SGD |
||
| GO:0006464 |
protein modification process |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006810 |
transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From SGD |
||
| GO:0006913 |
nucleocytoplasmic transport |
SGD_REF:S000046718 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006997 |
nucleus organization |
SGD_REF:S000046718 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0007067 |
mitosis |
SGD_REF:S000046718 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0008361 |
regulation of cell size |
SGD_REF:S000070190 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000114049 |
ISM: Inferred from Sequence Model |
C |
From SGD |
|||
| GO:0016567 |
protein ubiquitination |
SGD_REF:S000130860 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0016874 |
ligase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From SGD |
||
| GO:0016881 |
acid-amino acid ligase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
SGD_REF:S000146947 |
PANTHER:PTHR11254_AN0 |
P |
From SGD |
|||
| GO:0051028 |
mRNA transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0509 |
P |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Tabb AL et al. (2001) Genes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesis. Genetics 157: 1107-16 PubMed GONUTS page
- ↑ 2.0 2.1 Singh RK et al. (2009) Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis. Nat Cell Biol 11: 925-33 PubMed GONUTS page
- ↑ 3.0 3.1 Huh WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425: 686-91 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Utsugi T et al. (1999) Yeast tom1 mutant exhibits pleiotropic defects in nuclear division, maintenance of nuclear structure and nucleocytoplasmic transport at high temperatures. Gene 234: 285-95 PubMed GONUTS page
- ↑ Jorgensen P et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297: 395-400 PubMed GONUTS page
- ↑ De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
