GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:TIM18
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | TIM18 ( synonyms: YOR297C ) | |
| Protein Name(s) | Component of the mitochondrial TIM22 complex, | |
| External Links | ||
| SGD | S000005823 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001101 |
response to acid |
SGD_REF:S000124362 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0005506 |
iron ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000117178 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0496 |
C |
From SGD |
||
| GO:0005740 |
mitochondrial envelope |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005743 |
mitochondrial inner membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0999 |
C |
From SGD |
||
| GO:0005743 |
mitochondrial inner membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0168 |
C |
From SGD |
||
| GO:0006099 |
tricarboxylic acid cycle |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006810 |
transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0811 |
P |
From SGD |
||
| GO:0006915 |
apoptotic process |
SGD_REF:S000124362 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006970 |
response to osmotic stress |
SGD_REF:S000124362 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0015031 |
protein transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016021 |
integral to membrane |
SGD_REF:S000114049 |
ISM: Inferred from Sequence Model |
C |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From SGD |
||
| GO:0020037 |
heme binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0034599 |
cellular response to oxidative stress |
SGD_REF:S000124362 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0042721 |
mitochondrial inner membrane protein insertion complex |
SGD_REF:S000042844 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0042721 |
mitochondrial inner membrane protein insertion complex |
SGD_REF:S000049981 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0045039 |
protein import into mitochondrial inner membrane |
SGD_REF:S000042844 |
IGI: Inferred from Genetic Interaction |
SGD:S000003590 |
P |
From SGD |
||
| GO:0046685 |
response to arsenic-containing substance |
SGD_REF:S000124362 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
|
contributes_to |
GO:0015266 |
protein channel activity |
SGD_REF:S000072908 |
IDA: Inferred from Direct Assay |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Du L et al. (2007) Tim18, a component of the mitochondrial translocator, mediates yeast cell death induced by arsenic. Biochemistry (Mosc) 72: 843-7 PubMed GONUTS page
- ↑ Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
- ↑ De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
- ↑ 4.0 4.1 Kerscher O et al. (2000) Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol Biol Cell 11: 103-16 PubMed GONUTS page
- ↑ Koehler CM et al. (2000) Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane. Mol Cell Biol 20: 1187-93 PubMed GONUTS page
- ↑ Rehling P et al. (2003) Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science 299: 1747-51 PubMed GONUTS page
