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SGD:TIF5
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | TIF5 ( synonyms: YPR041W, SUI5 ) | |
| Protein Name(s) | Translation initiation factor eIF5, | |
| External Links | ||
| SGD | S000006245 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000054790 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000063195 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0396 |
F |
From SGD |
||
| GO:0005092 |
GDP-dissociation inhibitor activity |
SGD_REF:S000134638 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005092 |
GDP-dissociation inhibitor activity |
SGD_REF:S000134638 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0005096 |
GTPase activator activity |
SGD_REF:S000063195 |
IPI: Inferred from Physical Interaction |
F |
From SGD |
|||
| GO:0005096 |
GTPase activator activity |
SGD_REF:S000065405 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0005525 |
GTP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0342 |
F |
From SGD |
||
| GO:0006412 |
translation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0648 |
P |
From SGD |
||
| GO:0006413 |
translational initiation |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006413 |
translational initiation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0396 |
P |
From SGD |
||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000060440 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000060440 |
IPI: Inferred from Physical Interaction |
P |
From SGD |
|||
| GO:0016070 |
RNA metabolic process |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0022627 |
cytosolic small ribosomal subunit |
SGD_REF:S000043795 |
IPI: Inferred from Physical Interaction |
C |
From SGD |
|||
| GO:0042256 |
mature ribosome assembly |
SGD_REF:S000060440 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0043614 |
multi-eIF complex |
SGD_REF:S000082127 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0045947 |
negative regulation of translational initiation |
SGD_REF:S000134638 |
IGI: Inferred from Genetic Interaction |
SGD:S000002691 |
P |
From SGD |
||
| GO:0045947 |
negative regulation of translational initiation |
SGD_REF:S000134638 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chakravarti D & Maitra U (1993) Eukaryotic translation initiation factor 5 from Saccharomyces cerevisiae. Cloning, characterization, and expression of the gene encoding the 45,346-Da protein. J Biol Chem 268: 10524-33 PubMed GONUTS page
- ↑ 2.0 2.1 Das S et al. (1997) Specific interaction of eukaryotic translation initiation factor 5 (eIF5) with the beta-subunit of eIF2. J Biol Chem 272: 31712-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Jennings MD & Pavitt GD (2010) eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. Nature 465: 378-81 PubMed GONUTS page
- ↑ Das S et al. (2001) Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein. J Biol Chem 276: 6720-6 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Asano K et al. (2001) Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation. EMBO J 20: 2326-37 PubMed GONUTS page
- ↑ Phan L et al. (1998) Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5. Mol Cell Biol 18: 4935-46 PubMed GONUTS page
- ↑ Asano K et al. (2000) A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo. Genes Dev 14: 2534-46 PubMed GONUTS page
