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SGD:TIF2

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) TIF2 ( synonyms: YJL138C )
Protein Name(s) Translation initiation factor eIF4A,
External Links
SGD S000003674

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0001950

plasma membrane enriched fraction

SGD_REF:S000115094
PMID:16622836[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650
InterPro:IPR000629
InterPro:IPR011545

F

From SGD

GO:0003723

RNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From SGD

GO:0003743

translation initiation factor activity

SGD_REF:S000056288
PMID:2648398[2]

ISS: Inferred from Sequence or Structural Similarity

F

From SGD

GO:0003743

translation initiation factor activity

SGD_REF:S000056536
PMID:1502180[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003743

translation initiation factor activity

SGD_REF:S000058753
PMID:9841679[4]

TAS: Traceable Author Statement

F

From SGD

GO:0003743

translation initiation factor activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0396

F

From SGD

GO:0004004

ATP-dependent RNA helicase activity

SGD_REF:S000056536
PMID:1502180[3]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0347

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000629
InterPro:IPR001650
InterPro:IPR011545

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005737

cytoplasm

SGD_REF:S000056288
PMID:2648398[2]

ISS: Inferred from Sequence or Structural Similarity

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000069459
PMID:11914276[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0005840

ribosome

SGD_REF:S000058753
PMID:9841679[4]

TAS: Traceable Author Statement

C

From SGD

GO:0006412

translation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0648

P

From SGD

GO:0006413

translational initiation

SGD_REF:S000058753
PMID:9841679[4]

TAS: Traceable Author Statement

P

From SGD

GO:0006413

translational initiation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0396

P

From SGD

GO:0006446

regulation of translational initiation

SGD_REF:S000056288
PMID:2648398[2]

ISS: Inferred from Sequence or Structural Similarity

P

From SGD

GO:0008026

ATP-dependent helicase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011545
InterPro:IPR000629

F

From SGD

GO:0016281

eukaryotic translation initiation factor 4F complex

SGD_REF:S000056288
PMID:2648398[2]

IGI: Inferred from Genetic Interaction

C

From SGD

GO:0016281

eukaryotic translation initiation factor 4F complex

SGD_REF:S000056288
PMID:2648398[2]

ISS: Inferred from Sequence or Structural Similarity

C

From SGD

GO:0016281

eukaryotic translation initiation factor 4F complex

SGD_REF:S000056385
PMID:10409745[6]

IGI: Inferred from Genetic Interaction

C

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Delom F et al. (2006) The plasma membrane proteome of Saccharomyces cerevisiae and its response to the antifungal calcofluor. Proteomics 6: 3029-39 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Linder P & Slonimski PP (1989) An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutation. Proc Natl Acad Sci U S A 86: 2286-90 PubMed GONUTS page
  3. 3.0 3.1 Blum S et al. (1992) ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89: 7664-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 McCarthy JE (1998) Posttranscriptional control of gene expression in yeast. Microbiol Mol Biol Rev 62: 1492-553 PubMed GONUTS page
  5. Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
  6. Neff CL & Sachs AB (1999) Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally. Mol Cell Biol 19: 5557-64 PubMed GONUTS page
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