GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:SWH1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | SWH1 ( synonyms: YAR042W, OSH1, YAR044W ) | |
| Protein Name(s) | Protein similar to mammalian oxysterol-binding protein, | |
| External Links | ||
| SGD | S000000081 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000138 |
Golgi trans cisterna |
SGD_REF:S000060812 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0000139 |
Golgi membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0134 |
C |
From SGD |
||
| GO:0005543 |
phospholipid binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005545 |
1-phosphatidylinositol binding |
SGD_REF:S000059993 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAD46924 |
F |
From SGD |
||
| GO:0005545 |
1-phosphatidylinositol binding |
SGD_REF:S000071353 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAA59973.1 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005635 |
nuclear envelope |
SGD_REF:S000073325 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005640 |
nuclear outer membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0183 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0086 |
C |
From SGD |
||
| GO:0005769 |
early endosome |
SGD_REF:S000060812 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005783 |
endoplasmic reticulum |
SGD_REF:S000073325 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005794 |
Golgi apparatus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0333 |
C |
From SGD |
||
| GO:0006810 |
transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From SGD |
||
| GO:0006869 |
lipid transport |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0445 |
P |
From SGD |
||
| GO:0006887 |
exocytosis |
SGD_REF:S000118968 |
IGI: Inferred from Genetic Interaction |
SGD:S000001711 |
P |
From SGD |
||
| GO:0006897 |
endocytosis |
SGD_REF:S000115030 |
IGI: Inferred from Genetic Interaction |
SGD:S000001115 |
P |
From SGD |
||
| GO:0008142 |
oxysterol binding |
SGD_REF:S000059993 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAA31427 |
F |
From SGD |
||
| GO:0008289 |
lipid binding |
SGD_REF:S000132766 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0008289 |
lipid binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0446 |
F |
From SGD |
||
| GO:0015248 |
sterol transporter activity |
SGD_REF:S000132766 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0015918 |
sterol transport |
SGD_REF:S000114867 |
IGI: Inferred from Genetic Interaction |
SGD:S000006066 |
P |
From SGD |
||
| GO:0015918 |
sterol transport |
SGD_REF:S000132766 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0030011 |
maintenance of cell polarity |
SGD_REF:S000118968 |
IGI: Inferred from Genetic Interaction |
SGD:S000004219 |
P |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Levine TP & Munro S (2001) Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction. Mol Biol Cell 12: 1633-44 PubMed GONUTS page
- ↑ 2.0 2.1 Beh CT et al. (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157: 1117-40 PubMed GONUTS page
- ↑ Levine TP & Munro S (1998) The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes. Curr Biol 8: 729-39 PubMed GONUTS page
- ↑ 4.0 4.1 Loewen CJ et al. (2003) A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP. EMBO J 22: 2025-35 PubMed GONUTS page
- ↑ 5.0 5.1 Kozminski KG et al. (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7: 1224-42 PubMed GONUTS page
- ↑ Beh CT & Rine J (2004) A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution. J Cell Sci 117: 2983-96 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Schulz TA et al. (2009) Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues. J Cell Biol 187: 889-903 PubMed GONUTS page
- ↑ Raychaudhuri S et al. (2006) Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides. J Cell Biol 173: 107-19 PubMed GONUTS page
