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SGD:STE50

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) STE50 ( synonyms: YCL032W )
Protein Name(s) Protein involved in mating response,
External Links
SGD S000000537

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000161

MAPK cascade involved in osmosensory signaling pathway

SGD_REF:S000065130
PMID:9742096[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000161

MAPK cascade involved in osmosensory signaling pathway

SGD_REF:S000065130
PMID:9742096[1]

IPI: Inferred from Physical Interaction

SGD:S000004354

P

From SGD

GO:0000750

pheromone-dependent signal transduction involved in conjugation with cellular fusion

SGD_REF:S000053027
PMID:8793874[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000750

pheromone-dependent signal transduction involved in conjugation with cellular fusion

SGD_REF:S000053027
PMID:8793874[2]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0001402

signal transduction involved in filamentous growth

SGD_REF:S000049635
PMID:9738877[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0001402

signal transduction involved in filamentous growth

SGD_REF:S000049635
PMID:9738877[3]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0005737

cytoplasm

SGD_REF:S000065130
PMID:9742096[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0007049

cell cycle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From SGD

GO:0007050

cell cycle arrest

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0338

P

From SGD

GO:0007165

signal transduction

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000159

P

From SGD

GO:0007232

osmosensory signaling pathway via Sho1 osmosensor

SGD_REF:S000060320
PMID:11370856[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0019236

response to pheromone

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0589

P

From SGD

GO:0019887

protein kinase regulator activity

SGD_REF:S000049071
PMID:10397774[5]

IDA: Inferred from Direct Assay

F

From SGD

GO:0019887

protein kinase regulator activity

SGD_REF:S000049071
PMID:10397774[5]

IPI: Inferred from Physical Interaction

F

From SGD

GO:0032093

SAM domain binding

SGD_REF:S000113831
PMID:16337230[6]

IDA: Inferred from Direct Assay

F

From SGD

GO:0034605

cellular response to heat

SGD_REF:S000072547
PMID:12455951[7]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Posas F et al. (1998) Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway. Mol Cell Biol 18: 5788-96 PubMed GONUTS page
  2. 2.0 2.1 Xu G et al. (1996) Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae. Mol Microbiol 20: 773-83 PubMed GONUTS page
  3. 3.0 3.1 Ramezani Rad M et al. (1998) Ste50p is involved in regulating filamentous growth in the yeast Saccharomyces cerevisiae and associates with Ste11p. Mol Gen Genet 259: 29-38 PubMed GONUTS page
  4. Jansen G et al. (2001) Mutations in the SAM domain of STE50 differentially influence the MAPK-mediated pathways for mating, filamentous growth and osmotolerance in Saccharomyces cerevisiae. Mol Genet Genomics 265: 102-17 PubMed GONUTS page
  5. 5.0 5.1 Wu C et al. (1999) Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae. Mol Biol Cell 10: 2425-40 PubMed GONUTS page
  6. Kwan JJ et al. (2006) Saccharomyces cerevisiae Ste50 binds the MAPKKK Ste11 through a head-to-tail SAM domain interaction. J Mol Biol 356: 142-54 PubMed GONUTS page
  7. Winkler A et al. (2002) Heat stress activates the yeast high-osmolarity glycerol mitogen-activated protein kinase pathway, and protein tyrosine phosphatases are essential under heat stress. Eukaryot Cell 1: 163-73 PubMed GONUTS page
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