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SGD:STE2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | STE2 ( synonyms: YFL026W ) | |
| Protein Name(s) | Receptor for alpha-factor pheromone, | |
| External Links | ||
| SGD | S000001868 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000750 |
pheromone-dependent signal transduction involved in conjugation with cellular fusion |
SGD_REF:S000043707 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000755 |
cytogamy |
SGD_REF:S000121944 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0000755 |
cytogamy |
SGD_REF:S000121944 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0004871 |
signal transducer activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From SGD |
||
| GO:0004872 |
receptor activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From SGD |
||
| GO:0004930 |
G-protein coupled receptor activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From SGD |
||
| GO:0004932 |
mating-type factor pheromone receptor activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
SGD_REF:S000042026 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
SGD_REF:S000042841 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
SGD_REF:S000048542 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
SGD_REF:S000056023 |
IGI: Inferred from Genetic Interaction |
SGD:S000003846 |
F |
From SGD |
||
| GO:0004934 |
mating-type alpha-factor pheromone receptor activity |
SGD_REF:S000056023 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0005624 |
membrane fraction |
SGD_REF:S000122673 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005887 |
integral to plasma membrane |
SGD_REF:S000049330 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0007165 |
signal transduction |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From SGD |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0162 |
C |
From SGD |
||
| GO:0016021 |
integral to membrane |
SGD_REF:S000114049 |
ISM: Inferred from Sequence Model |
C |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From SGD |
||
| GO:0019236 |
response to pheromone |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0589 |
P |
From SGD |
||
| GO:0030031 |
cell projection assembly |
SGD_REF:S000071985 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0051260 |
protein homooligomerization |
SGD_REF:S000115835 |
IPI: Inferred from Physical Interaction |
SGD:S000001868 |
P |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Jenness DD et al. (1987) Saccharomyces cerevisiae mutants unresponsive to alpha-factor pheromone: alpha-factor binding and extragenic suppression. Mol Cell Biol 7: 1311-9 PubMed GONUTS page
- ↑ 2.0 2.1 Shi C et al. (2007) A role for a complex between activated G protein-coupled receptors in yeast cellular mating. Proc Natl Acad Sci U S A 104: 5395-400 PubMed GONUTS page
- ↑ Blumer KJ & Thorner J (1990) Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc Natl Acad Sci U S A 87: 4363-7 PubMed GONUTS page
- ↑ Burkholder AC & Hartwell LH (1985) The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res 13: 8463-75 PubMed GONUTS page
- ↑ Jenness DD et al. (1983) Binding of alpha-factor pheromone to yeast a cells: chemical and genetic evidence for an alpha-factor receptor. Cell 35: 521-9 PubMed GONUTS page
- ↑ 6.0 6.1 Dosil M et al. (1998) Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments. Mol Cell Biol 18: 5981-91 PubMed GONUTS page
- ↑ Aronova S et al. (2007) Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae. Mol Biol Cell 18: 2779-94 PubMed GONUTS page
- ↑ Blumer KJ et al. (1988) The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae. J Biol Chem 263: 10836-42 PubMed GONUTS page
- ↑ De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
- ↑ Vallier LG et al. (2002) The alpha-factor receptor C-terminus is important for mating projection formation and orientation in Saccharomyces cerevisiae. Cell Motil Cytoskeleton 53: 251-66 PubMed GONUTS page
- ↑ Gehret AU et al. (2006) Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors. J Biol Chem 281: 20698-714 PubMed GONUTS page
