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SGD:SRP1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) SRP1 ( synonyms: YNL189W, KAP60, SCM1 )
Protein Name(s) Karyopherin alpha homolog,
External Links
SGD S000005133

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005634

nucleus

SGD_REF:S000041520
PMID:10725229[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000069459
PMID:11914276[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002652
InterPro:IPR024931

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000041520
PMID:10725229[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR024931
InterPro:IPR002652

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0006606

protein import into nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR024931
InterPro:IPR002652

P

From SGD

GO:0006606

protein import into nucleus

SGD_REF:S000128919
PMID:19141610[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006612

protein targeting to membrane

SGD_REF:S000123937
PMID:16929305[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006810

transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From SGD

GO:0008565

protein transporter activity

SGD_REF:S000046571
PMID:7622450[5]

IDA: Inferred from Direct Assay

F

From SGD

GO:0008565

protein transporter activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002652
InterPro:IPR024931

F

From SGD

GO:0015031

protein transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[6]

ISM: Inferred from Sequence Model

C

From SGD

GO:0048471

perinuclear region of cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0198

C

From SGD

colocalizes_with

GO:0000176

nuclear exosome (RNase complex)

SGD_REF:S000128567
PMID:19046973[7]

IDA: Inferred from Direct Assay

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Hood JK et al. (2000) Nup2p is located on the nuclear side of the nuclear pore complex and coordinates Srp1p/importin-alpha export. J Cell Sci 113 ( Pt 8): 1471-80 PubMed GONUTS page
  2. Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
  3. MacKinnon MA et al. (2009) The Kap60-Kap95 karyopherin complex directly regulates phosphatidylcholine synthesis. J Biol Chem 284: 7376-84 PubMed GONUTS page
  4. King MC et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442: 1003-7 PubMed GONUTS page
  5. Enenkel C et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J Biol Chem 270: 16499-502 PubMed GONUTS page
  6. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
  7. Synowsky SA et al. (2009) Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. J Mol Biol 385: 1300-13 PubMed GONUTS page
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