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SGD:SPT2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | SPT2 ( synonyms: YER161C, EXA1, SIN1 ) | |
| Protein Name(s) | Protein involved in negative regulation of transcription, | |
| External Links | ||
| SGD | S000000963 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
SGD_REF:S000122834 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000217 |
DNA secondary structure binding |
SGD_REF:S000081418 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000043877 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000043877 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0006325 |
chromatin organization |
SGD_REF:S000114296 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006325 |
chromatin organization |
SGD_REF:S000128515 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0006368 |
transcription elongation from RNA polymerase II promoter |
SGD_REF:S000114296 |
IGI: Inferred from Genetic Interaction |
SGD:S000000483 |
P |
From SGD |
||
| GO:0043631 |
RNA polyadenylation |
SGD_REF:S000116779 |
IGI: Inferred from Genetic Interaction |
SGD:S000000834 |
P |
From SGD |
||
| GO:0043631 |
RNA polyadenylation |
SGD_REF:S000116779 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Dobi KC & Winston F (2007) Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae. Mol Cell Biol 27: 5575-86 PubMed GONUTS page
- ↑ Novoseler M et al. (2005) Functional domains of the yeast chromatin protein Sin1p/Spt2p can bind four-way junction and crossing DNA structures. J Biol Chem 280: 5169-77 PubMed GONUTS page
- ↑ 3.0 3.1 Kruger W & Herskowitz I (1991) A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1. Mol Cell Biol 11: 4135-46 PubMed GONUTS page
- ↑ 4.0 4.1 Nourani A et al. (2006) Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae. Mol Cell Biol 26: 1496-509 PubMed GONUTS page
- ↑ Sikdar N et al. (2008) Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway. PLoS Genet 4: e1000290 PubMed GONUTS page
- ↑ 6.0 6.1 Hershkovits G et al. (2006) Recruitment of mRNA cleavage/polyadenylation machinery by the yeast chromatin protein Sin1p/Spt2p. Proc Natl Acad Sci U S A 103: 9808-13 PubMed GONUTS page
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