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SGD:SGF73

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) SGF73 ( synonyms: YGL066W, SCA7 )
Protein Name(s) SAGA complex subunit,
External Links
SGD S000003034

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000124

SAGA complex

SGD_REF:S000070225
PMID:12052880[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000124

SAGA complex

SGD_REF:S000081847
PMID:15932941[2]

IPI: Inferred from Physical Interaction

SGD:S000002856
SGD:S000002552

C

From SGD

GO:0000124

SAGA complex

SGD_REF:S000119604
PMID:17090597[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005198

structural molecule activity

SGD_REF:S000081847
PMID:15932941[2]

IGI: Inferred from Genetic Interaction

UniProtKB:O15265

F

From SGD

GO:0005198

structural molecule activity

SGD_REF:S000081847
PMID:15932941[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0006406

mRNA export from nucleus

SGD_REF:S000126522
PMID:18488019[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006461

protein complex assembly

SGD_REF:S000129354
PMID:19226466[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008047

enzyme activator activity

SGD_REF:S000126522
PMID:18488019[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0008047

enzyme activator activity

SGD_REF:S000134005
PMID:20434206[6]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0016568

chromatin modification

SGD_REF:S000081847
PMID:15932941[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016568

chromatin modification

SGD_REF:S000119604
PMID:17090597[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016573

histone acetylation

SGD_REF:S000070225
PMID:12052880[1]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0016573

histone acetylation

SGD_REF:S000081847
PMID:15932941[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016578

histone deubiquitination

SGD_REF:S000129354
PMID:19226466[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0045899

positive regulation of RNA polymerase II transcriptional preinitiation complex assembly

SGD_REF:S000119604
PMID:17090597[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0046695

SLIK (SAGA-like) complex

SGD_REF:S000081847
PMID:15932941[2]

IPI: Inferred from Physical Interaction

SGD:S000002552
SGD:S000002856

C

From SGD

GO:0071819

DUBm complex

SGD_REF:S000134402
PMID:20395473[7]

IDA: Inferred from Direct Assay

C

From SGD

contributes_to

GO:0004402

histone acetyltransferase activity

SGD_REF:S000081847
PMID:15932941[2]

IMP: Inferred from Mutant Phenotype

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Sanders SL et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22: 4723-38 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 McMahon SJ et al. (2005) Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity. Proc Natl Acad Sci U S A 102: 8478-82 PubMed GONUTS page
  3. 3.0 3.1 3.2 Shukla A et al. (2006) SAGA-associated Sgf73p facilitates formation of the preinitiation complex assembly at the promoters either in a HAT-dependent or independent manner in vivo. Nucleic Acids Res 34: 6225-32 PubMed GONUTS page
  4. 4.0 4.1 Köhler A et al. (2008) Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export. Nat Cell Biol 10: 707-15 PubMed GONUTS page
  5. 5.0 5.1 Lee KK et al. (2009) Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes. Epigenetics Chromatin 2: 2 PubMed GONUTS page
  6. Köhler A et al. (2010) Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module. Cell 141: 606-17 PubMed GONUTS page
  7. Samara NL et al. (2010) Structural insights into the assembly and function of the SAGA deubiquitinating module. Science 328: 1025-9 PubMed GONUTS page
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