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SGD:SEN2

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) SEN2 ( synonyms: YLR105C )
Protein Name(s) Subunit of the tRNA splicing endonuclease,
External Links
SGD S000004095

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000213

tRNA-intron endonuclease activity

PMID:17352735[1]

IMP: Inferred from Mutant Phenotype

F

Fig 2 shows sen2 gave least amount of pre-tRNA, i.e. shows the tRNA splicing function of the gene.

complete

GO:0000213

tRNA-intron endonuclease activity

SGD_REF:S000049224
PMID:2182322[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0000213

tRNA-intron endonuclease activity

SGD_REF:S000049482
PMID:9200603[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0000213

tRNA-intron endonuclease activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR016589
InterPro:IPR006677
InterPro:IPR006676

F

From SGD

GO:0000213

tRNA-intron endonuclease activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:3.1.27.9

F

From SGD

GO:0000214

tRNA-intron endonuclease complex

SGD_REF:S000049482
PMID:9200603[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000214

tRNA-intron endonuclease complex

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR016589

C

From SGD

GO:0000379

tRNA-type intron splice site recognition and cleavage

SGD_REF:S000049224
PMID:2182322[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000379

tRNA-type intron splice site recognition and cleavage

SGD_REF:S000049482
PMID:9200603[3]

IDA: Inferred from Direct Assay

P

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011856

F

From SGD

GO:0004518

nuclease activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011856

F

From SGD

GO:0004518

nuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From SGD

GO:0004519

endonuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0255

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

From SGD

GO:0005741

mitochondrial outer membrane

SGD_REF:S000076331
PMID:12925762[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005741

mitochondrial outer membrane

SGD_REF:S000076331
PMID:12925762[5]

IMP: Inferred from Mutant Phenotype

C

From SGD

GO:0005741

mitochondrial outer membrane

SGD_REF:S000114057
PMID:16407407[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005741

mitochondrial outer membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1000

C

From SGD

GO:0005741

mitochondrial outer membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0172

C

From SGD

GO:0006388

tRNA splicing, via endonucleolytic cleavage and ligation

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006677
InterPro:IPR006676
InterPro:IPR016589

P

From SGD

GO:0008033

tRNA processing

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0819

P

From SGD

GO:0012505

endomembrane system

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0147

C

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0090305

nucleic acid phosphodiester bond hydrolysis

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011856

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Yoshihisa T et al. (2007) Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae. Genes Cells 12: 285-97 PubMed GONUTS page
  2. 2.0 2.1 Ho CK et al. (1990) Accumulation of pre-tRNA splicing '2/3' intermediates in a Saccharomyces cerevisiae mutant. EMBO J 9: 1245-52 PubMed GONUTS page
  3. 3.0 3.1 3.2 Trotta CR et al. (1997) The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases. Cell 89: 849-58 PubMed GONUTS page
  4. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  5. 5.0 5.1 Yoshihisa T et al. (2003) Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria. Mol Biol Cell 14: 3266-79 PubMed GONUTS page
  6. Zahedi RP et al. (2006) Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell 17: 1436-50 PubMed GONUTS page
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