GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:SEN1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | SEN1 ( synonyms: YLR430W, CIK3, NRD2 ) | |
| Protein Name(s) | Presumed helicase required for RNA pol II transcription termination, | |
| External Links | ||
| SGD | S000004422 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0004386 |
helicase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004386 |
helicase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000044234 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0006364 |
rRNA processing |
SGD_REF:S000046278 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006364 |
rRNA processing |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006364 |
rRNA processing |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0698 |
P |
From SGD |
||
| GO:0006369 |
termination of RNA polymerase II transcription |
SGD_REF:S000119984 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006369 |
termination of RNA polymerase II transcription |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006378 |
mRNA polyadenylation |
SGD_REF:S000147631 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006397 |
mRNA processing |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0507 |
P |
From SGD |
||
| GO:0008033 |
tRNA processing |
SGD_REF:S000046278 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0008033 |
tRNA processing |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0008033 |
tRNA processing |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0819 |
P |
From SGD |
||
| GO:0008094 |
DNA-dependent ATPase activity |
SGD_REF:S000054111 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0008186 |
RNA-dependent ATPase activity |
SGD_REF:S000054111 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0016180 |
snRNA processing |
SGD_REF:S000046278 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016180 |
snRNA processing |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0032575 |
ATP-dependent 5'-3' RNA helicase activity |
SGD_REF:S000054111 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0035649 |
Nrd1 complex |
SGD_REF:S000119452 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0043141 |
ATP-dependent 5'-3' DNA helicase activity |
SGD_REF:S000054111 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0043144 |
snoRNA processing |
SGD_REF:S000046278 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0043144 |
snoRNA processing |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ursic D et al. (1995) Inactivation of the yeast Sen1 protein affects the localization of nucleolar proteins. Mol Gen Genet 249: 571-84 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Ursic D et al. (1997) The yeast SEN1 gene is required for the processing of diverse RNA classes. Nucleic Acids Res 25: 4778-85 PubMed GONUTS page
- ↑ Steinmetz EJ et al. (2006) Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase. Mol Cell 24: 735-46 PubMed GONUTS page
- ↑ Beggs S et al. (2012) The PolyA tail length of yeast histone mRNAs varies during the cell cycle and is influenced by Sen1p and Rrp6p. Nucleic Acids Res 40: 2700-11 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Kim HD et al. (1999) The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase. Biochemistry 38: 14697-710 PubMed GONUTS page
- ↑ Vasiljeva L & Buratowski S (2006) Nrd1 interacts with the nuclear exosome for 3' processing of RNA polymerase II transcripts. Mol Cell 21: 239-48 PubMed GONUTS page
