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SGD:SEC2

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) SEC2 ( synonyms: YNL272C )
Protein Name(s) Guanyl-nucleotide exchange factor for the small G-protein Sec4p,
External Links
SGD S000005216

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005085

guanyl-nucleotide exchange factor activity

SGD_REF:S000051492
PMID:9199166[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005085

guanyl-nucleotide exchange factor activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

F

From SGD

GO:0005829

cytosol

SGD_REF:S000069949
PMID:12045183[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005934

cellular bud tip

SGD_REF:S000134800
PMID:20493815[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005934

cellular bud tip

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0030

C

From SGD

GO:0005935

cellular bud neck

SGD_REF:S000134800
PMID:20493815[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005935

cellular bud neck

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0029

C

From SGD

GO:0006810

transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From SGD

GO:0006887

exocytosis

SGD_REF:S000069949
PMID:12045183[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006914

autophagy

SGD_REF:S000133980
PMID:20444978[4]

IGI: Inferred from Genetic Interaction

SGD:S000001889

P

From SGD

GO:0006914

autophagy

SGD_REF:S000133980
PMID:20444978[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0015031

protein transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From SGD

GO:0030133

transport vesicle

SGD_REF:S000069949
PMID:12045183[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0030133

transport vesicle

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0244

C

From SGD

GO:0031410

cytoplasmic vesicle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0968

C

From SGD

GO:0043332

mating projection tip

SGD_REF:S000128539
PMID:19053807[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0070273

phosphatidylinositol-4-phosphate binding

SGD_REF:S000134800
PMID:20493815[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0070273

phosphatidylinositol-4-phosphate binding

SGD_REF:S000134800
PMID:20493815[3]

IMP: Inferred from Mutant Phenotype

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Walch-Solimena C et al. (1997) Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J Cell Biol 137: 1495-509 PubMed GONUTS page
  2. 2.0 2.1 2.2 Ortiz D et al. (2002) Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast. J Cell Biol 157: 1005-15 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Mizuno-Yamasaki E et al. (2010) Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p. Dev Cell 18: 828-40 PubMed GONUTS page
  4. 4.0 4.1 Geng J et al. (2010) Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell 21: 2257-69 PubMed GONUTS page
  5. Narayanaswamy R et al. (2009) Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast. J Proteome Res 8: 6-19 PubMed GONUTS page
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