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SGD:SEC17

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) SEC17 ( synonyms: YBL050W, RNS3 )
Protein Name(s) Peripheral membrane protein required for ER/Golgi vesicular transport,
External Links
SGD S000000146

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000300

peripheral to membrane of membrane fraction

SGD_REF:S000043228
PMID:1601878[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0001671

ATPase activator activity

SGD_REF:S000041605
PMID:10387016[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005483

soluble NSF attachment protein activity

SGD_REF:S000041605
PMID:10387016[2]

IPI: Inferred from Physical Interaction

SGD:S000000284

F

From SGD

GO:0005483

soluble NSF attachment protein activity

SGD_REF:S000072047
PMID:11994317[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005622

intracellular

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000744

C

From SGD

GO:0005829

cytosol

SGD_REF:S000046174
PMID:8636207[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006810

transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From SGD

GO:0006886

intracellular protein transport

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000744

P

From SGD

GO:0006914

autophagy

SGD_REF:S000066273
PMID:11694599[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0015031

protein transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016020

membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0162

C

From SGD

GO:0016192

vesicle-mediated transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0931

P

From SGD

GO:0031201

SNARE complex

SGD_REF:S000049070
PMID:10397773[6]

IPI: Inferred from Physical Interaction

SGD:S000002876
SGD:S000005378
SGD:S000004810

C

From SGD

GO:0035494

SNARE complex disassembly

SGD_REF:S000127173
PMID:18650938[7]

IDA: Inferred from Direct Assay

P

From SGD

GO:0042144

vacuole fusion, non-autophagic

SGD_REF:S000052275
PMID:9685264[8]

IDA: Inferred from Direct Assay

P

From SGD

GO:0042144

vacuole fusion, non-autophagic

SGD_REF:S000053100
PMID:8670830[9]

IDA: Inferred from Direct Assay

P

From SGD

GO:0048280

vesicle fusion with Golgi apparatus

SGD_REF:S000043228
PMID:1601878[1]

IDA: Inferred from Direct Assay

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Griff IC et al. (1992) The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein. J Biol Chem 267: 12106-15 PubMed GONUTS page
  2. 2.0 2.1 Steel GJ et al. (1999) Biochemical analysis of the Saccharomyces cerevisiae SEC18 gene product: implications for the molecular mechanism of membrane fusion. Biochemistry 38: 7764-72 PubMed GONUTS page
  3. Peng R & Gallwitz D (2002) Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes. J Cell Biol 157: 645-55 PubMed GONUTS page
  4. Lupashin VV et al. (1996) Biochemical requirements for the targeting and fusion of ER-derived transport vesicles with purified yeast Golgi membranes. J Cell Biol 132: 277-89 PubMed GONUTS page
  5. Ishihara N et al. (2001) Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion. Mol Biol Cell 12: 3690-702 PubMed GONUTS page
  6. Coe JG et al. (1999) A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae. Mol Biol Cell 10: 2407-23 PubMed GONUTS page
  7. Mima J et al. (2008) Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones. EMBO J 27: 2031-42 PubMed GONUTS page
  8. Sato K & Wickner W (1998) Functional reconstitution of ypt7p GTPase and a purified vacuole SNARE complex. Science 281: 700-2 PubMed GONUTS page
  9. Haas A & Wickner W (1996) Homotypic vacuole fusion requires Sec17p (yeast alpha-SNAP) and Sec18p (yeast NSF). EMBO J 15: 3296-305 PubMed GONUTS page
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