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SGD:SCS2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | SCS2 ( synonyms: YER120W ) | |
| Protein Name(s) | Integral ER membrane protein that regulates phospholipid metabolism, | |
| External Links | ||
| SGD | S000000922 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005198 |
structural molecule activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005635 |
nuclear envelope |
SGD_REF:S000073325 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005783 |
endoplasmic reticulum |
SGD_REF:S000073325 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005783 |
endoplasmic reticulum |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From SGD |
||
| GO:0005789 |
endoplasmic reticulum membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0097 |
C |
From SGD |
||
| GO:0005934 |
cellular bud tip |
SGD_REF:S000124647 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006348 |
chromatin silencing at telomere |
SGD_REF:S000060389 |
IGI: Inferred from Genetic Interaction |
SGD:S000002259 |
P |
From SGD |
||
| GO:0006348 |
chromatin silencing at telomere |
SGD_REF:S000060389 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006348 |
chromatin silencing at telomere |
SGD_REF:S000071547 |
IGI: Inferred from Genetic Interaction |
SGD:S000002200 |
P |
From SGD |
||
| GO:0008654 |
phospholipid biosynthetic process |
SGD_REF:S000043021 |
IGI: Inferred from Genetic Interaction |
SGD:S000001863 |
P |
From SGD |
||
| GO:0008654 |
phospholipid biosynthetic process |
SGD_REF:S000051398 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0008654 |
phospholipid biosynthetic process |
SGD_REF:S000073194 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016021 |
integral to membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From SGD |
||
| GO:0030176 |
integral to endoplasmic reticulum membrane |
SGD_REF:S000051398 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0031965 |
nuclear membrane |
SGD_REF:S000051398 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0031965 |
nuclear membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0182 |
C |
From SGD |
||
| GO:0032377 |
regulation of intracellular lipid transport |
SGD_REF:S000073325 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0033149 |
FFAT motif binding |
SGD_REF:S000073325 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0033149 |
FFAT motif binding |
SGD_REF:S000073325 |
IPI: Inferred from Physical Interaction |
SGD:S000001012 |
F |
From SGD |
||
| GO:0035091 |
phosphatidylinositol binding |
SGD_REF:S000124601 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0042992 |
negative regulation of transcription factor import into nucleus |
SGD_REF:S000073325 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0042992 |
negative regulation of transcription factor import into nucleus |
SGD_REF:S000073325 |
IPI: Inferred from Physical Interaction |
SGD:S000001012 |
P |
From SGD |
||
| GO:0048309 |
endoplasmic reticulum inheritance |
SGD_REF:S000124647 |
IGI: Inferred from Genetic Interaction |
SGD:S000001352 |
P |
From SGD |
||
| GO:0048309 |
endoplasmic reticulum inheritance |
SGD_REF:S000124647 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Loewen CJ et al. (2003) A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP. EMBO J 22: 2025-35 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Loewen CJ et al. (2007) Inheritance of cortical ER in yeast is required for normal septin organization. J Cell Biol 179: 467-83 PubMed GONUTS page
- ↑ 3.0 3.1 Craven RJ & Petes TD (2001) The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. Genetics 158: 145-54 PubMed GONUTS page
- ↑ Cuperus G & Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162: 633-45 PubMed GONUTS page
- ↑ Nikawa J et al. (1995) Cloning and sequence of the SCS2 gene, which can suppress the defect of INO1 expression in an inositol auxotrophic mutant of Saccharomyces cerevisiae. J Biochem 118: 39-45 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Kagiwada S et al. (1998) The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism. J Bacteriol 180: 1700-8 PubMed GONUTS page
- ↑ Kagiwada S & Zen R (2003) Role of the yeast VAP homolog, Scs2p, in INO1 expression and phospholipid metabolism. J Biochem 133: 515-22 PubMed GONUTS page
- ↑ Kagiwada S & Hashimoto M (2007) The yeast VAP homolog Scs2p has a phosphoinositide-binding ability that is correlated with its activity. Biochem Biophys Res Commun 364: 870-6 PubMed GONUTS page
