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SGD:RVB2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | RVB2 ( synonyms: YPL235W, TIH2, TIP48, TIP49B ) | |
| Protein Name(s) | ATP-dependent DNA helicase, also known as reptin, | |
| External Links | ||
| SGD | S000006156 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0000492 |
box C/D snoRNP assembly |
SGD_REF:S000066250 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000492 |
box C/D snoRNP assembly |
SGD_REF:S000136091 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000812 |
Swr1 complex |
SGD_REF:S000074662 |
IPI: Inferred from Physical Interaction |
SGD:S000002742 |
C |
From SGD |
||
| GO:0000812 |
Swr1 complex |
SGD_REF:S000075430 |
IPI: Inferred from Physical Interaction |
SGD:S000004505 |
C |
From SGD |
||
| GO:0000812 |
Swr1 complex |
SGD_REF:S000113597 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0003678 |
DNA helicase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004386 |
helicase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000066250 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005654 |
nucleoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0190 |
C |
From SGD |
||
| GO:0006281 |
DNA repair |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From SGD |
||
| GO:0006338 |
chromatin remodeling |
SGD_REF:S000075430 |
IPI: Inferred from Physical Interaction |
SGD:S000004505 |
P |
From SGD |
||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
SGD_REF:S000060643 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006364 |
rRNA processing |
SGD_REF:S000066250 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006364 |
rRNA processing |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0698 |
P |
From SGD |
||
| GO:0006974 |
response to DNA damage stimulus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From SGD |
||
| GO:0016568 |
chromatin modification |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0156 |
P |
From SGD |
||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0017111 |
nucleoside-triphosphatase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0031011 |
Ino80 complex |
SGD_REF:S000040657 |
IPI: Inferred from Physical Interaction |
SGD:S000003118 |
C |
From SGD |
||
| GO:0032508 |
DNA duplex unwinding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
SGD_REF:S000134452 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0043141 |
ATP-dependent 5'-3' DNA helicase activity |
SGD_REF:S000125377 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0043486 |
histone exchange |
SGD_REF:S000074662 |
IPI: Inferred from Physical Interaction |
SGD:S000002742 |
P |
From SGD |
||
| GO:0070209 |
ASTRA complex |
SGD_REF:S000128493 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0097255 |
R2TP complex |
SGD_REF:S000081009 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0097255 |
R2TP complex |
SGD_REF:S000136091 |
IPI: Inferred from Physical Interaction |
SGD:S000002598 |
C |
From SGD |
||
|
colocalizes_with |
GO:0005724 |
nuclear telomeric heterochromatin |
SGD_REF:S000147574 |
IDA: Inferred from Direct Assay |
C |
From SGD |
||
|
contributes_to |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
SGD_REF:S000040657 |
IDA: Inferred from Direct Assay |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 King TH et al. (2001) A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins. Mol Cell Biol 21: 7731-46 PubMed GONUTS page
- ↑ 2.0 2.1 Zhao R et al. (2008) Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol 180: 563-78 PubMed GONUTS page
- ↑ 3.0 3.1 Mizuguchi G et al. (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303: 343-8 PubMed GONUTS page
- ↑ 4.0 4.1 Krogan NJ et al. (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12: 1565-76 PubMed GONUTS page
- ↑ Wu WH et al. (2005) Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange. Nat Struct Mol Biol 12: 1064-71 PubMed GONUTS page
- ↑ Jónsson ZO et al. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276: 16279-88 PubMed GONUTS page
- ↑ 7.0 7.1 Shen X et al. (2000) A chromatin remodelling complex involved in transcription and DNA processing. Nature 406: 541-4 PubMed GONUTS page
- ↑ Papin C et al. (2010) 3'- to 5' DNA unwinding by TIP49b proteins. FEBS J 277: 2705-14 PubMed GONUTS page
- ↑ Gribun A et al. (2008) Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex. J Mol Biol 376: 1320-33 PubMed GONUTS page
- ↑ Shevchenko A et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9: R167 PubMed GONUTS page
- ↑ Zhao R et al. (2005) Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. Cell 120: 715-27 PubMed GONUTS page
- ↑ Grandin N & Charbonneau M (2011) Rvb2/reptin physically associates with telomerase in budding yeast. FEBS Lett 585: 3890-7 PubMed GONUTS page