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SGD:RSC3

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) RSC3 ( synonyms: YDR303C )
Protein Name(s) Component of the RSC chromatin remodeling complex,
External Links
SGD S000002711

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000082

G1/S transition of mitotic cell cycle

SGD_REF:S000122982
PMID:17542652[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000086

G2/M transition of mitotic cell cycle

SGD_REF:S000122982
PMID:17542652[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000981

sequence-specific DNA binding RNA polymerase II transcription factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001138

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000060732
PMID:11336698[2]

ISS: Inferred from Sequence or Structural Similarity

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0005634

nucleus

SGD_REF:S000069459
PMID:11914276[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001138

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006337

nucleosome disassembly

SGD_REF:S000127685
PMID:16492771[4]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000060732
PMID:11336698[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001138

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0006357

regulation of transcription from RNA polymerase II promoter

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001138

P

From SGD

GO:0006366

transcription from RNA polymerase II promoter

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001138

P

From SGD

GO:0006368

transcription elongation from RNA polymerase II promoter

SGD_REF:S000119500
PMID:17081996[5]

IDA: Inferred from Direct Assay

P

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001138

F

From SGD

GO:0016568

chromatin modification

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0156

P

From SGD

GO:0016584

nucleosome positioning

SGD_REF:S000144470
PMID:21343911[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016586

RSC complex

SGD_REF:S000055568
PMID:10619019[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0016586

RSC complex

SGD_REF:S000060732
PMID:11336698[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033262

regulation of DNA replication involved in S phase

SGD_REF:S000122982
PMID:17542652[1]

IGI: Inferred from Genetic Interaction

SGD:S000004313

P

From SGD

GO:0043044

ATP-dependent chromatin remodeling

SGD_REF:S000074929
PMID:12183366[8]

IDA: Inferred from Direct Assay

P

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000128778
PMID:19111667[9]

IDA: Inferred from Direct Assay

F

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000129025
PMID:19158363[10]

IDA: Inferred from Direct Assay

F

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD

GO:0051726

regulation of cell cycle

SGD_REF:S000060732
PMID:11336698[2]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0051726

regulation of cell cycle

SGD_REF:S000060732
PMID:11336698[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

contributes_to

GO:0015616

DNA translocase activity

SGD_REF:S000074929
PMID:12183366[8]

IDA: Inferred from Direct Assay

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Campsteijn C et al. (2007) Reverse genetic analysis of the yeast RSC chromatin remodeler reveals a role for RSC3 and SNF5 homolog 1 in ploidy maintenance. PLoS Genet 3: e92 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Angus-Hill ML et al. (2001) A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control. Mol Cell 7: 741-51 PubMed GONUTS page
  3. Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
  4. Lorch Y et al. (2006) Chromatin remodeling by nucleosome disassembly in vitro. Proc Natl Acad Sci U S A 103: 3090-3 PubMed GONUTS page
  5. Carey M et al. (2006) RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation. Mol Cell 24: 481-7 PubMed GONUTS page
  6. Wippo CJ et al. (2011) The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes. EMBO J 30: 1277-88 PubMed GONUTS page
  7. Cairns BR et al. (1999) Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Mol Cell 4: 715-23 PubMed GONUTS page
  8. 8.0 8.1 Saha A et al. (2002) Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes Dev 16: 2120-34 PubMed GONUTS page
  9. Badis G et al. (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32: 878-87 PubMed GONUTS page
  10. Zhu C et al. (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19: 556-66 PubMed GONUTS page
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