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SGD:RPN1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | RPN1 ( synonyms: YHR027C, HRD2, NAS1 ) | |
| Protein Name(s) | Base subunit of the 19S regulatory particle of the 26S proteasome, | |
| External Links | ||
| SGD | S000001069 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000502 |
proteasome complex |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0000502 |
proteasome complex |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0647 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000079924 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005737 |
cytoplasm |
SGD_REF:S000069459 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005783 |
endoplasmic reticulum |
SGD_REF:S000069459 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
SGD_REF:S000058010 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
SGD_REF:S000058463 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0008540 |
proteasome regulatory particle, base subcomplex |
SGD_REF:S000039974 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0030234 |
enzyme regulator activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0030674 |
protein binding, bridging |
SGD_REF:S000071480 |
IPI: Inferred from Physical Interaction |
F |
From SGD |
|||
| GO:0030674 |
protein binding, bridging |
SGD_REF:S000074998 |
IPI: Inferred from Physical Interaction |
SGD:S000000763 |
F |
From SGD |
||
| GO:0034515 |
proteasome storage granule |
SGD_REF:S000126567 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0042176 |
regulation of protein catabolic process |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0050790 |
regulation of catalytic activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
|
contributes_to |
GO:0004175 |
endopeptidase activity |
SGD_REF:S000058010 |
TAS: Traceable Author Statement |
F |
From SGD |
||
|
contributes_to |
GO:0004175 |
endopeptidase activity |
SGD_REF:S000058463 |
TAS: Traceable Author Statement |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wendler P et al. (2004) The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions. J Biol Chem 279: 37751-62 PubMed GONUTS page
- ↑ 2.0 2.1 Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
- ↑ 3.0 3.1 Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30: 405-39 PubMed GONUTS page
- ↑ 4.0 4.1 Finley D et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23: 244-5 PubMed GONUTS page
- ↑ Glickman MH et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94: 615-23 PubMed GONUTS page
- ↑ Saeki Y et al. (2002) Identification of ubiquitin-like protein-binding subunits of the 26S proteasome. Biochem Biophys Res Commun 296: 813-9 PubMed GONUTS page
- ↑ Elsasser S et al. (2002) Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 4: 725-30 PubMed GONUTS page
- ↑ Laporte D et al. (2008) Reversible cytoplasmic localization of the proteasome in quiescent yeast cells. J Cell Biol 181: 737-45 PubMed GONUTS page
