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SGD:RPA12

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) RPA12 ( synonyms: YJR063W, RRN4 )
Protein Name(s) RNA polymerase I subunit A12.2,
External Links
SGD S000003824

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003674

molecular function

SGD_REF:S000069584

ND: No biological Data available

F

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001222

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001529

F

From SGD

GO:0003899

DNA-directed RNA polymerase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001529
InterPro:IPR012164

F

From SGD

GO:0003899

DNA-directed RNA polymerase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0240

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005730

nucleolus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0188

C

From SGD

GO:0005736

DNA-directed RNA polymerase I complex

SGD_REF:S000048222
PMID:8417319[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005736

DNA-directed RNA polymerase I complex

SGD_REF:S000054011
PMID:9837969[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005736

DNA-directed RNA polymerase I complex

SGD_REF:S000065940
PMID:11486042[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001529
InterPro:IPR001222
InterPro:IPR012164

P

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0240
UniProtKB-KW:KW-0804

P

From SGD

GO:0006363

termination of RNA polymerase I transcription

SGD_REF:S000075993
PMID:15073335[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006363

termination of RNA polymerase I transcription

SGD_REF:S000126113
PMID:18413718[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR012164
InterPro:IPR001222

F

From SGD

GO:0042790

transcription of nuclear large rRNA transcript from RNA polymerase I promoter

SGD_REF:S000055971
PMID:1871118[6]

IGI: Inferred from Genetic Interaction

SGD:S000006486

P

From SGD

GO:0042790

transcription of nuclear large rRNA transcript from RNA polymerase I promoter

SGD_REF:S000058088
PMID:9121426[7]

IGI: Inferred from Genetic Interaction

SGD:S000003684
SGD:S000002563
SGD:S000005192
SGD:S000006486

P

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Nogi Y et al. (1993) Gene RRN4 in Saccharomyces cerevisiae encodes the A12.2 subunit of RNA polymerase I and is essential only at high temperatures. Mol Cell Biol 13: 114-22 PubMed GONUTS page
  2. Keener J et al. (1998) Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription. J Biol Chem 273: 33795-802 PubMed GONUTS page
  3. Briand JF et al. (2001) Partners of Rpb8p, a small subunit shared by yeast RNA polymerases I, II and III. Mol Cell Biol 21: 6056-65 PubMed GONUTS page
  4. Prescott EM et al. (2004) Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p. Proc Natl Acad Sci U S A 101: 6068-73 PubMed GONUTS page
  5. Kawauchi J et al. (2008) Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination. Genes Dev 22: 1082-92 PubMed GONUTS page
  6. Nogi Y et al. (1991) An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 88: 7026-30 PubMed GONUTS page
  7. Gadal O et al. (1997) A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine. Mol Cell Biol 17: 1787-95 PubMed GONUTS page
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