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SGD:ROT2

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ROT2 ( synonyms: YBR229C, GLS2 )
Protein Name(s) Glucosidase II catalytic subunit involved in cell wall synthesis,
External Links
SGD S000000433

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011013

F

From SGD

GO:0004553

hydrolase activity, hydrolyzing O-glycosyl compounds

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000322

F

From SGD

GO:0004558

alpha-glucosidase activity

SGD_REF:S000053239
PMID:9430631[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005739

mitochondrion

SGD_REF:S000075100
PMID:14576278[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000064885
PMID:8910335[4]

ISS: Inferred from Sequence or Structural Similarity

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0095

C

From SGD

GO:0005788

endoplasmic reticulum lumen

SGD_REF:S000113928
PMID:16373354[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005975

carbohydrate metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011013
InterPro:IPR000322

P

From SGD

GO:0008152

metabolic process

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0326

P

From SGD

GO:0009272

fungal-type cell wall biogenesis

SGD_REF:S000053239
PMID:9430631[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0016798

hydrolase activity, acting on glycosyl bonds

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0326

F

From SGD

GO:0017177

glucosidase II complex

SGD_REF:S000113928
PMID:16373354[5]

IPI: Inferred from Physical Interaction

SGD:S000002629

C

From SGD

GO:0030246

carbohydrate binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011013

F

From SGD

GO:0033919

glucan 1,3-alpha-glucosidase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:3.2.1.84

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Simons JF et al. (1998) Cell wall 1,6-beta-glucan synthesis in Saccharomyces cerevisiae depends on ER glucosidases I and II, and the molecular chaperone BiP/Kar2p. EMBO J 17: 396-405 PubMed GONUTS page
  2. Sickmann A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100: 13207-12 PubMed GONUTS page
  3. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  4. Trombetta ES et al. (1996) Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit. J Biol Chem 271: 27509-16 PubMed GONUTS page
  5. 5.0 5.1 Wilkinson BM et al. (2006) Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum. J Biol Chem 281: 6325-33 PubMed GONUTS page
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