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SGD:RNH70

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) RNH70 ( synonyms: YGR276C, REX1, RNA82 )
Protein Name(s) 3'-5' exoribonuclease,
External Links
SGD S000003508

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000175

3'-5'-exoribonuclease activity

SGD_REF:S000044002
PMID:10716935[1]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0000467

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

SGD_REF:S000044002
PMID:10716935[1]

IGI: Inferred from Genetic Interaction

SGD:S000004097
SGD:S000004049

P

From SGD

GO:0002107

generation of mature 3'-end of 5S rRNA generated by RNA polymerase III

SGD_REF:S000044002
PMID:10716935[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR012337

F

From SGD

GO:0003723

RNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From SGD

GO:0004518

nuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From SGD

GO:0004527

exonuclease activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006055

F

From SGD

GO:0004527

exonuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

F

From SGD

GO:0005622

intracellular

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006055

C

From SGD

GO:0005634

nucleus

SGD_REF:S000052595
PMID:10359084[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006364

rRNA processing

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0698

P

From SGD

GO:0008033

tRNA processing

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0819

P

From SGD

GO:0008408

3'-5' exonuclease activity

SGD_REF:S000044092
PMID:9396823[3]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P0A784

F

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0034415

tRNA 3'-trailer cleavage, exonucleolytic

SGD_REF:S000044002
PMID:10716935[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0034415

tRNA 3'-trailer cleavage, exonucleolytic

SGD_REF:S000126376
PMID:18456844[4]

IGI: Inferred from Genetic Interaction

SGD:S000002209

P

From SGD

GO:0034415

tRNA 3'-trailer cleavage, exonucleolytic

SGD_REF:S000126376
PMID:18456844[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0034476

U5 snRNA 3'-end processing

SGD_REF:S000044002
PMID:10716935[1]

IGI: Inferred from Genetic Interaction

SGD:S000004097
SGD:S000004049

P

From SGD

GO:0042254

ribosome biogenesis

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0690

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 van Hoof A et al. (2000) Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J 19: 1357-65 PubMed GONUTS page
  2. Frank P et al. (1999) Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene. FEBS Lett 450: 251-6 PubMed GONUTS page
  3. Moser MJ et al. (1997) The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains. Nucleic Acids Res 25: 5110-8 PubMed GONUTS page
  4. 4.0 4.1 Copela LA et al. (2008) Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation. RNA 14: 1214-27 PubMed GONUTS page
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