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SGD:RAD5

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) RAD5 ( synonyms: YLR032W, REV2, SNM2 )
Protein Name(s) DNA helicase proposed to promote replication fork regression,
External Links
SGD S000004022

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0000209

protein polyubiquitination

SGD_REF:S000131367
PMID:19706603[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0000400

four-way junction DNA binding

SGD_REF:S000124451
PMID:17936713[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0000403

Y-form DNA binding

SGD_REF:S000124451
PMID:17936713[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0000790

nuclear chromatin

SGD_REF:S000042429
PMID:10880451[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650
InterPro:IPR014905

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000330

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0347

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000330
InterPro:IPR001650

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0006281

DNA repair

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From SGD

GO:0006301

postreplication repair

SGD_REF:S000124451
PMID:17936713[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006302

double-strand break repair

SGD_REF:S000086919
PMID:16224103[4]

IGI: Inferred from Genetic Interaction

SGD:S000005194
SGD:S000004837
SGD:S000002777

P

From SGD

GO:0006302

double-strand break repair

SGD_REF:S000086919
PMID:16224103[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006974

response to DNA damage stimulus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From SGD

GO:0008094

DNA-dependent ATPase activity

SGD_REF:S000124451
PMID:17936713[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001841
InterPro:IPR014905

F

From SGD

GO:0009378

four-way junction helicase activity

SGD_REF:S000124451
PMID:17936713[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0010994

free ubiquitin chain polymerization

SGD_REF:S000131367
PMID:19706603[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0016818

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR014905

F

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Carlile CM et al. (2009) Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5. J Biol Chem 284: 29326-34 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Blastyák A et al. (2007) Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression. Mol Cell 28: 167-75 PubMed GONUTS page
  3. Ulrich HD & Jentsch S (2000) Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 19: 3388-97 PubMed GONUTS page
  4. 4.0 4.1 Chen S et al. (2005) The RING finger ATPase Rad5p of Saccharomyces cerevisiae contributes to DNA double-strand break repair in a ubiquitin-independent manner. Nucleic Acids Res 33: 5878-86 PubMed GONUTS page
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