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SGD:RAD2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | RAD2 ( synonyms: YGR258C ) | |
| Protein Name(s) | Single-stranded DNA endonuclease, | |
| External Links | ||
| SGD | S000003490 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000014 |
single-stranded DNA specific endodeoxyribonuclease activity |
SGD_REF:S000045977 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0000112 |
nucleotide-excision repair factor 3 complex |
SGD_REF:S000044877 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003697 |
single-stranded DNA binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003824 |
catalytic activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004518 |
nuclease activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004518 |
nuclease activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0540 |
F |
From SGD |
||
| GO:0004519 |
endonuclease activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004519 |
endonuclease activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0255 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0006281 |
DNA repair |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006281 |
DNA repair |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From SGD |
||
| GO:0006289 |
nucleotide-excision repair |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006295 |
nucleotide-excision repair, DNA incision, 3'-to lesion |
SGD_REF:S000054237 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006295 |
nucleotide-excision repair, DNA incision, 3'-to lesion |
SGD_REF:S000054237 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006366 |
transcription from RNA polymerase II promoter |
SGD_REF:S000070302 |
IGI: Inferred from Genetic Interaction |
SGD:S000003796 |
P |
From SGD |
||
| GO:0006974 |
response to DNA damage stimulus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From SGD |
||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0016788 |
hydrolase activity, acting on ester bonds |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Habraken Y et al. (1993) Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease. Nature 366: 365-8 PubMed GONUTS page
- ↑ Habraken Y et al. (1996) Transcription factor TFIIH and DNA endonuclease Rad2 constitute yeast nucleotide excision repair factor 3: implications for nucleotide excision repair and Cockayne syndrome. Proc Natl Acad Sci U S A 93: 10718-22 PubMed GONUTS page
- ↑ 3.0 3.1 Harrington JJ & Lieber MR (1994) Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair. Genes Dev 8: 1344-55 PubMed GONUTS page
- ↑ Lee SK et al. (2002) Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome. Cell 109: 823-34 PubMed GONUTS page